نتایج جستجو برای: releasing hormone antagonist

تعداد نتایج: 213193  

Journal: :Animal reproduction science 2007
H Jiménez-Severiano M J D'Occhio D D Lunstra M L Mussard T L Davis W J Enright J E Kinder

The objective was to compare the relative response between rams and bulls in characteristics of LH, FSH and testosterone (T) secretion, during and after long-term treatment with GnRH analogs. Animals were treated with GnRH agonist, GnRH antagonist, or vehicle (Control) for 28 days. Serial blood samples were collected on day 21 of treatment, and at several intervals after treatment. Injections o...

Journal: :Human reproduction 2007
J A Huirne R Homburg C B Lambalk

We believe that appropriate comparison of optimal GnRH agonist and antagonist regimens has not been performed yet. Currently available meta-analyses included all comparative studies between GnRH agonists and antagonists performed so far, including less than optimal GnRH antagonist regimens. After critical appraisal of the various studied GnRH antagonist regimens in terms of follicular developme...

2014
Yujing Xiong Zhiqin Bu Wei Dai Meixiang Zhang Xiao Bao Yingpu Sun

The objective of this meta-analysis is to assess the impact of LH supplementation in women undergoing in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) with gonadotropin releasing hormone (GnRH) antagonist protocol. No significant difference in outcomes between LH supplementation and r-FSH alone in women undergoing IVF/ICSI with GnRH antagonist protocol is currently present, a...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
C G Ziegler J W Brown A V Schally A Erler L Gebauer A Treszl L Young L M Fishman J B Engel H S Willenberg S Petersenn G Eisenhofer M Ehrhart-Bornstein S R Bornstein

Peptide analogues targeting various neuropeptide receptors have been used effectively in cancer therapy. A hallmark of adrenocortical tumor formation is the aberrant expression of peptide receptors relating to uncontrolled cell proliferation and hormone overproduction. Our microarray results have also demonstrated a differential expression of neuropeptide hormone receptors in tumor subtypes of ...

Journal: :nephro-urology monthly 0
farid fazeli uro-oncology research center, tehran university of medical sciences, tehran, ir iran mohammad reza nowroozi uro-oncology research center, tehran university of medical sciences, tehran, ir iran; uro-oncology research center, tehran university of medical sciences, tehran, ir iran. tel: +98-2166903063, fax: +98-2166903063 mohsen ayati uro-oncology research center, tehran university of medical sciences, tehran, ir iran sahar latifi brain and spinal cord injury research center, neuroscience institute, tehran university of medical sciences, tehran, ir iran mohsen taheri mahmoodi uro-oncology research center, tehran university of medical sciences, tehran, ir iran abbas norouzi javidan brain and spinal cord injury research center, neuroscience institute, tehran university of medical sciences, tehran, ir iran

conclusions our study showed that microrelin is as effective as diphereline in reducing psa and testosterone and can be recommended to initiate medical castration in patients with pc. results each group contained 40 patients. in group a, psa was reduced from 75.78 ± 72.43 ng/ml to 1.93 ± 1.40 ng/ml after 6 months and testosterone was reduced from 3.50 ± 1.12 nmol/l to 0.81 ± 0.05 nmol/l. there ...

Journal: :Expert review of pharmacoeconomics & outcomes research 2013
Hind T Hatoum E David Crawford Sandy Kildegaard Nielsen Swu-Jane Lin Dennis C Marshall

Degarelix, approved in the USA in 2008, is a gonadotropin-releasing hormone antagonist, representing one of the latest additions to androgen deprivation therapy (ADT). ADT is used as first-line therapy for locally advanced or metastatic prostate cancer with the aim to reduce testosterone to castrate levels. Like other gonadotropin-releasing hormone-antagonists, degarelix treatment results in ra...

Journal: :The Canadian journal of urology 2015
Jack Barkin

Several abstracts presented at the 2015 European Association of Urology Meeting highlighted new developments in hormone therapy for prostate cancer management. One abstract described how the luteinizing hormone-releasing hormone (LHRH)/gonadotropin-releasing hormone (GnRH) agonist leuprolide, but not the LHRH/GnRH antagonist degarelix, induced plaque instability in a mouse model. A second abstr...

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