background: gonadotropin-releasing hormone (gnrh) plays essential roles in embryo implantation, invasion of trophoblastic tissue, and steroid synthesis in the placenta. objective: the aim of this study was to evaluate the effect of gnrh antagonist administration on pregnancy outcomes in early implantation period. materials and methods: in this retrospective study, 94 infertile women undergoing ...

te Amsterdam.

BACKGROUND The aim of this study was to assess the effect of an individualized GnRH antagonist regimen on folliculogenesis. METHODS In a multicentre, randomized, clinical trial, IVF/ICSI patients were allocated to a standard regimen, in which they received daily 0.25 mg GnRH antagonist ganirelix (Orgalutran) from the 6th day of stimulation onward (fixed regimen n = 102) or to an individualize...

Corticotrophin-releasing hormone is a key regulator of the mammalian stress response. Although its actions on behavior are well documented, the actions of corticotrophin-releasing hormone in cortical neuronal systems are poorly understood. In the present experiments, adult male Sprague-Dawley rats were anesthetized and field excitatory post-synaptic potential recordings were made from sensorimo...

The use of progesterone for luteal support in stimulated cycles for in-vitro fertilization is well established. However, the benefits of the addition of estradiol are still controversial. The aim of this study was to compare ongoing pregnancy rates in patients stimulated with recombinant follicle stimulating hormone and gonadotrophin releasing hormone antagonist for in vitro fertilization, who ...

Whole-cell patch-clamp and extracellular field recordings were obtained from 450-microns-thick brain slices of infant rats (10-13 days postnatal) to determine the actions of corticotropin-releasing hormone on glutamate- and GABA-mediated synaptic transmission in the hippocampus. Synthetic corticotropin-releasing hormone (0.15 microM) reversibly increased the excitability of hippocampal pyramida...