A periodic-review, random-demand inventory model is analyzed under the assumption that replenishment quantities are random fractions of the amounts ordered. Results of a previous study of a single-period model are generalized to form an easily computed heuristic adaptation of the (s, S) policy for use in this environment. The heuristic is based on the simple practice of scaling down pipeline in...

AIMS Glycosaminoglycan (GAG) layer replenishment is a cornerstone in the therapy of interstitial cystitis (IC). During the last years intravesical GAG layer replenishment has proven to be an effective treatment for overactive bladder (OAB), radiation cystitis, and recurrent urinary tract infections (UTIs). METHODS Examination of different substances available for intravesical GAG replenishmen...

Although vesicle replenishment is critical in maintaining exo-endocytosis recycling, the underlying mechanisms are not well understood. Previous studies have shown that both rapid and slow endocytosis recycle into a very large recycling pool instead of within the readily releasable pool (RRP), and the time course of RRP replenishment is slowed down by more intense stimulation. This finding cont...

T such as radio-frequency identification and global positioning systems can provide improved real-time tracking information for products and replenishment orders along the supply chain. We call this type of visibility order progress information. In this paper, we investigate how order progress information can be used to improve inventory replenishment decisions. To this end, we examine a retail...

In this research, we deal with VMI (Vendor Managed Inventory) problem where one supplier is responsible for managing a retailer’s inventory under unstable customer demand situation. To cope with the nonstationary demand situation, we develop a retrospective action-reward learning model, a kind of reinforcement learning techniques, which is faster in learning than conventional action-reward lear...

This paper presents a multi-product multi-period inventory problem with random replenishment intervals and fuzzy costs under space and shortage level constraints. Since the costs (purchasing, holding and backordering) related to inventory system are often imprecise and the replenishment intervals are random in real life, the proposed model is also fuzzy-random Here, the replenishment intervals ...

This paper considers the ranking of alternative replenishment policies for a single-location inventory when customer demand is con"ned to a single product. It is supposed that customer demand is uncertain and described by imprecise linguistic terms de"ned by fuzzy sets. For example, `demand is about da, or `demand is more or less between d and d a, or more complex `demand is about d, but there ...