background: this study aimed to compare the percentage of detection of periarthritis in patients with rheumatoid arthritis using clinical examination and ultrasound methods. materials and methods: this study is a cross?sectional study which was conducted in al?zahra hospital (isfahan, iran) during 2014–2015. in our study, ninety patients were selected based on the american college of rheumatolo...

Cathepsin K is a cysteine protease that plays an essential role in osteoclast function and in the degradation of protein components of the bone matrix by cleaving proteins such as collagen type I, collagen type II and osteonectin. Cathepsin K therefore plays a role in bone remodelling and resorption in diseases such as osteoporosis, osteolytic bone metastasis and rheumatoid arthritis. We examin...

BACKGROUND Osteoporosis and related fragility fractures are one of the most common complications seen in patients with rheumatoid arthritis (RA) and dramatically affect quality of life. OBJECTIVE To evaluate changes in bone mineral density in patients with recent onset rheumatoid arthritis (<1 year) and its correlation if any with a modified DAS-28 score and simple erosion narrowing score (SE...

BACKGROUND Quantitative ultrasound (QUS) is a reliable tool for discriminating between subjects with and without vertebral deformities in postmenopausal osteoporosis. Less is known about osteoporosis caused by inflammatory diseases or corticosteroid use. OBJECTIVES (1). To compare in patients with rheumatoid arthritis the ability of QUS and dual energy x ray absorptiometry (DXA) to discrimina...

References BARNETr, E., AND NORDIN, B. E. C. (1960) Clin. Radiol., 11, 166 (The radiological diagnosis of osteoporosis-a new approach) KENNEDY, A. C., SMrrH, D. A., BUCHANAN, W. W., ANDERSON, J. B., SAMUELS, B. B., AND JASANI, M. K. (1974) 'Osteoporosis in rheumatoid arthritis' in 'R' International review of the Ligue Internationale Centre Le Rhumatisme. SMrrH, D. A. (1971) Osteoporosis. Thesis...

Rheumatoid arthritis may be associated with generalised as well as periarticular osteoporosis. To assess the extent of bone loss and the influence of corticosteroid treatment total body calcium was measured by in-vivo neutron activation analysis in 63 patients with rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs alone and 31 treated with additional low-dose corticosteroi...

References BARNETr, E., AND NORDIN, B. E. C. (1960) Clin. Radiol., 11, 166 (The radiological diagnosis of osteoporosis-a new approach) KENNEDY, A. C., SMrrH, D. A., BUCHANAN, W. W., ANDERSON, J. B., SAMUELS, B. B., AND JASANI, M. K. (1974) 'Osteoporosis in rheumatoid arthritis' in 'R' International review of the Ligue Internationale Centre Le Rhumatisme. SMrrH, D. A. (1971) Osteoporosis. Thesis...