STUDY DESIGN Cross-sectional study. PURPOSE To investigate the relationship between ligamentum flavum (LF) thickening and lumbar segmental instability and disc degeneration and facet joint osteoarthritis. OVERVIEW OF LITERATURE Posterior spinal structures, including LF thickness, play a major role in lumbar spinal canal stenosis pathogenesis. The cause of LF thickening is multifactorial and...

To judge about the performance of designed support system for tunnels, structural forces i.e. peak values of axial and shear forces and moments are critical parameters. So in this study, at first a complete database using finite element method was prepared. Then, a model of artificial neural network (ANN) using multi-layer perceptron was developed to estimate lining structural forces. Sensitivi...

OBJECTIVE To observe the therapeutic effects of segmental resection and decompression combined with joint prosthesis on continuous knee osteoarthritis (OA). METHODS A total of 130 patients with knee OA were selected and randomly divided into an observation group and a control group (n=65). The control group was treated by segmental resection in combination with joint prosthesis, and the obser...

The tunnel lining segments are assumed to be rigid, and the tensile, compression, shear, bending properties of joints considered. A simplified calculation method for dynamic response structure under ground shock is proposed, its correctness verified by comparing it with results from finite element method. Using this method, a subway calculated, change in joint force studied, influence angle bet...

assessment of tunnel face stability in unsaturated media based on limit analysis method mohammad amin nozari; mohammad maleki; behnam yousefi             analysis of the causes of contractor’s claims in the db contracts of underground projects in iran hadi talkhabi; majid parchami jalal; mahmood golabchi                         quality assessment of segmental lining installation in mechanized e...

OBJECTIVES To analyse the mononuclear cell populations in synovial membrane biopsies obtained before treatment from patients with rheumatoid arthritis (RA) and to correlate the findings with the degree of joint damage occurring over one year. METHODS Multiple needle biopsy specimens were obtained from inflamed knee joints on entry to the study. The tissue samples were examined using immunohis...

OBJECTIVES Current methods of monitoring chronic synovitis in a single joint rely on clinical examination derived indices, such as the detection of synovial thickening. This study aimed to develop a reproducible method for quantifying the volume of synovial lining in chronic synovitis using contrast enhanced magnetic resonance (MR) imaging. METHODS The knees of 18 patients with chronic synovi...

Uridine diphosphoglucose dehydrogenase (UDPGD) is the enzyme responsible for the production of uridine diphospho(UDP)-glucuronate, an essential monosaccharide in the biosynthesis of hyaluronan, which is found in high concentrations in normal synovial fluid. Synovial lining cells have been implicated in the synthesis of hyaluronan, but the degree to which they are adapted metabolically to this f...

OBJECTIVE In experimental collagenase-induced osteoarthritis (OA) in the mouse, synovial lining macrophages are crucial in mediating joint destruction. It was recently shown that adipose-derived stem cells (ASCs) express immunosuppressive characteristics. This study was undertaken to explore the effect of intraarticular injection of ASCs on synovial lining thickness and its relation to joint pa...