Background: Bilateral synchronous testis germ cell tumors with different histopathology are not common. Case Presentation: Here, a case of 27-year-old male who is reported presented with bilateral testicular swellings. There was a high α-fetoprotein level with bilateral lesions on scrotal USG. Bilateral orchiectomy was performed. According to pathology report, there was a right testicular semi...

Spermatocytic Seminoma (SS) is less common than the Classic variant, as its incidence ranges between 1.3% and 2.3% of all seminomas. Generally SS is diagnosed in men older than 50 years. The Anaplastic variant of Spermatocytic Seminoma is characterized by an earlier onset when compared to SS, but a benign behavior in spite of its histological patterns similar to Classic Seminoma. We reported th...

Cryptorchidism is a very common anomaly, affecting 2-4% of male infants and is more common in premature infants. The long-term outcome despite orchidopexy still remains problematic and controversial with a risk of developing cancer 5-10 times greater than normal. Paratesticular tumors are mostly benign and very rare in children however malignant paratesticular tumors do arise, the most common b...

Reaction to Yadav S et al: Invalid presentation of bilateral synchronous spermatocytic seminoma Kanika Sharma, Piyush Kalakoti, Kush Ohri, Suman Sahu, Sreenivas Veeranki Rural Medical College, Pravara Institute of Medical Sciences, Loni, MH 413736, India,Pushpanjali Crosslay Hospital, Ghaziabad, UP 201012, India, University of Texas Medical Branch, Galveston, TX, United States of America Corres...

AIM To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. METHOD We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy . RESULTS A total of 85 patients were included. The median follow-up was 15 years. The 20-year overall survival (OS) and relap...

Despite the apparent link between the presence of alkaline phosphatase (ALP) and various cancers, it has so far been difficult to determine distinct differences between seminoma-derived ALP and placental ALP (PLAP). In order to determine specificity, we purified ALP from a seminoma type of human testicular cancer tissue and compared its biochemical and immunological properties with those of PLA...

Primary mediastinal seminoma is an uncommon tumor usually located in the anterior mediastinum. The majority of cases occur in young males. We report here an extremely rare case of a 69-year-old male with primary seminoma in the middle mediastinum. The patient had no complaints, but an abnormal shadow was seen in a routine chest X-ray. We performed a tumorectomy in the middle mediastinum, a thym...

We report a histologically pure stage 1 seminoma with an elevated human chorionic gonadotropin (hCG). A 38 year-old man was referred for the evaluation of the left testicular swelling. He showed an elevated serum hCG level of 25,265 mIU/ml with normal a fetoprotein and lactate dehydrogenase. Imaging showed heterogeneous tumor without any metastatic lesions. We conducted 4 courses of chemotherap...

introduction: Seminoma comprises ~50% of testicular germ cell tumors. Renal metastases are infrequent and are usually diagnosed at necropsy. Clinical case: A 24-year-old male with a history of left radical orchiectomy and adjuvant radiotherapy due to classic seminoma (stage I) showed elevated levels of b-human chorionic gonadotropin and lactate dehydrogenase during the 11-month follow-up. Compu...

Cryptorchidism is the most common predisposing factor in the development of testicular germ cell tumors. Seminoma is the most common malignancy developing in a cryptorchid testis, usually has lymphatic but rarely hematogenous metastasis. The Urinary Bladder is an extremely rare site of metastasis of seminoma metastasis. A 29-year-old male patient presented to us with a history of infertility an...