SMARCB1 (INI1)-deficient sinonasal carcinoma is a recently described variant of sinonasal tract carcinoma characterized by complete loss of nuclear SMARCB1 (INI1). It is very rare and currently underdiagnosed because of a lack of awareness. Before the description of SMARCB1 (INI1)-deficient sinonasal carcinomas, these tumors were probably misclassified as various malignant neoplasms. To date, o...

We describe the case of a 43-year-old man who was referred to our dental school"s acute care clinic with pain and swelling of presumed dental origin in the left maxillary quadrant. Radiographic examination revealed extensive dental decay and periodontal disease. On questioning, the patient admitted to paresthesia of recent onset. Paresthesia associated with pain or swelling of the jaws is an om...

Introduction: Sinonasal undifferentiated carcinoma is a scarce, highly aggressive however clinicopathologically distinctive tumor, which usually affects the superior nasal cavity or the paranasal sinuses. Case presentation: A 54-year-old man with left nasal obstruction and intermittent epistaxis was found on anterior rhinoscopy confirmed by nasal endoscopic examination with a reddish/grey friab...

BACKGROUND The management of sinonasal undifferentiated carcinoma (SNUC) remains unclear. Low incidence and poor outcomes make treatment standardization difficult. The objective of this study was to review the used treatment and our outcomes. METHODS From 2001 to 2013, 17 cases of SNUC were treated at our department. Charts were reviewed for standard demographic, tumour size and extension, hi...

Sinonasal undifferentiated carcinoma happens rarely, the clinical manifestations of the disease lacked specificity, with nasal obstruction and blood mainly in a unilateral nasal cavity. Two casas were reviewed, one case of tumor located in the middle of inferior turbinate; 1 in the bottom wall of the anterior nasal cavity. The tumor appeared dark red and unsmooth surface. Sinus CT scan showed o...

OBJECTIVE The study purpose was to detect the value of magnetic resonance imaging (MRI) compared to computed tomography (CT) and different imaging modalities as conventional radiology in evaluation of sinonasal neoplasms diagnosed by Histopathology. METHODS Thirty patients (16 males and 14 females) were complaining of symptoms related to sinonasal tract. After thorough clinical and local exam...

Glioblastoma Multiforme (GBM) is a high-grade brain tumour with the most dismal prognosis. There are very few reports on second malignancies occurring in GBM patients, as the survival has been short. Second malignancies have been reported after treatment of malignancies with radiation therapy and chemotherapy especially after 5 to 10 y of treatment. Here in, we present a very unique case where ...