introduction: skin dose and depth dose distribution of some beta sources that can contaminate skin or protective clothing covering the skin have been calculated using varskin2. materials and methods: in this research, absorbed dose to skin and depth dose from the skin surface have been calculated for 90sr/90y, 147pm, 32p beta emitter radioisotopes by using input parameters: activity of source, ...

Two-photon excitation fluorescence microscopy allows in vivo high-resolution imaging of human skin structure and biochemistry with a penetration depth over 100 microm. The major damage mechanism during two-photon skin imaging is associated with the formation of cavitation at the epidermal-dermal junction, which results in thermal mechanical damage of the tissue. In this report, we verify that t...

Two patients encountered a first-degree cold burn after use of a deodorant spray. The spray-nozzle to skin-surface distance was approximately 5 cm, and the spraying lasted approximately 15 seconds. Under laboratory conditions, the deodorant in use was able to induce a decline in temperature of >60 degrees C. These 2 cases highlight a little-known potential for skin damage by deodorant sprays if...

Nutritional protection against skin damage from sunlight is increasingly advocated to the general public, but its effectiveness is controversial. In this meta-analysis, we have systematically reviewed the existing literature on human supplementation studies on dietary protection against sunburn by beta-carotene. A review of literature until June 2007 was performed in PubMed, ISI Web of Science ...

Ultraviolet (UV) is one of the environmental pathogenic factors causing skin damage. Aiming to assess the risk of face skin exposure to UV irradiance from different rotation angles, a rotating model was used to monitor the exposure of the skin on the face to UV irradiance, with skin damage action spectra used to determine the biologically effective UV irradiance (UVBEskin) and UVBEskin radiant ...

BACKGROUND Exposure to sunlight may decrease the risk of several diseases through the synthesis of vitamin D, whereas solar radiation is the main cause of some skin and eye diseases. However, to the best of our knowledge, the association of sun-induced skin damage with mortality remains unknown. METHODOLOGY/PRINCIPAL FINDINGS Subjects were 8472 white participants aged 25-74 years in the First...

During adolescence, there is a steady decline in the use of sun protection and increased use of indoor tanning lights. Previous health education efforts have changed knowledge but not these behaviors. Middle school students (n=113) received a single educational class that included personal viewing of skin changes visible under ultraviolet (UV) filtered light. Pre-/post-surveys assessed past, cu...

The UVB component of solar radiation is a risk factor for skin cancer, the most common cancer in the Western world. Yet little is known about the induction of DNA damage in human skin by UVB and its modulation by sunscreens. Here, we apply a novel postlabeling high-performance liquid chromatography technique to quantify UVB-induced photoproducts in skin biopsies with and without sunscreen. The ...

Most skin cancers develop as the result of UV light-induced DNA damage; however, a substantial number of cases appear to occur independently of UV damage. A causal link between UV-independent skin cancers and chronic inflammation has been suspected, although the precise mechanism underlying this association is unclear. Here, we have proposed that activation-induced cytidine deaminase (AID, enco...