Skin wound healing is a complex and dynamic process that aims to restore lesioned tissues. Collagen-based skin substitutes are promising treatment promote by mimicking the native structure. Recently, collagen from marine organisms has gained interest as source for producing biomaterials regenerative strategies. This preliminary study aimed describe application of collagen-based skin-like scaffo...

Autologous epidermal cell cultures (CEA) represent a possibility to treat extensive burn lesions, since they allow a significative surface expansion which cannot be achieved with other surgical techniques based on autologous grafting. Moreover currently available CEA preparations are difficult to handle and their take rate is unpredictable. This study aimed at producing and evaluating a new cut...

OBJECTIVE To report on the clinical benefits of platelet gel application in a non-regenerating skin wound. CLINICAL PRESENTATION AND INTERVENTION An 84-year-old man presented with a severe wound with a regular circumference in the frontal region which resulted in a complete loss of epidermis and dermis. The skin lesion, induced by cryosurgery used to remove a basal-cell carcinoma, had previou...

Knowledge about the skin mechanical properties is essential in several domains, particularly for clinical applications and cosmetic industry. It can help to evaluate skin disease. The complex structure of the skin leads to complex mechanical behaviour [1, 2, 3]. The aim of this study was to measure the mechanical properties of the skin in the different directions and regions. The ethical and im...

Wound healing can be problematic in several clinical settings because of massive tissue injury (burns), wound healing deficiencies (chronic wounds), or congenital conditions and diseases. Engineered skin substitutes have been developed to address the medical need for wound coverage and tissue repair. Currently, no engineered skin substitute can replace all of the functions of intact human skin....

Introduction: Total Skin Electron Therapy (TSET) and Total Body Irradiation (TBI) are kinds of treatment which use electron and photon beams to treat special types of cancers. The aim of these techniques are to deliver uniform dose to the entire skin while minimizing delivered dose to organs at risk. To check the homogeneity of dose delivery in TBI and TSET, using a humanoid ph...