BACKGROUND Tumors of the skull base pose unique challenges to radiosurgical treatment because of their irregular shapes, proximity to critical structures and variable tumor volumes. In this study, we investigate whether acceptable treatment plans with excellent conformity and homogeneity can be generated for complex skull base tumors using the Cyberknife radiosurgical system. METHODS At Georg...

BACKGROUND The past two decades have been the setting for remarkable advancement in endonasal endoscopic neurosurgery. Refinements in camera definition, surgical instrumentation, navigation, and surgical technique, including the dual surgeon team, have facilitated purely endonasal endoscopic approaches to the majority of the midline skull base that were previously difficult to access through th...

the clivus is the surface of a portion of the occipital and sphenoid bones in the base of the skull. (1)it is surrounded by the neurovascular structures of the brainstem, as well as internal carotid arteries. tumors of the clivus can be benign (chordoma)or malignant (chondrosarcoma).(2) chordomas are rare, aggressive, slow-growing, invasive, and locally destructive tumors that arise from the no...

ollier’s syndrome, a variant of multiple enchondromatosis, is a rare disease with an estimated prevalence of 1/100,000, characterized by multiple enchondromas, asymmetrically involving small bones of the hands and feet, especially the proximal phalanges. intracranial enchondromas, such as those arising from the skull base are extremely rare. herein, we report a 25-year-old female, known case of...

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We reported a 71 years old woman, with history of rest and postural tremor, bradykinesia and memory problems. In her dynamic MRI, a contrastenhanced tumor in the cerebellopontine (CP) angle was found which was compatible with a meningioma. 99mTc-TRODAT SPECT showed decreased activity in the left putamen, indicating idiopathic Parkinson disease. There was also a focus of increased activity on th...

Brown tumor is a bone lesion secondary to hyperparathyroidism of various etiologies. Skeletal involvement in primary hyperparathyroidism secondary to parathyroid adenoma is very uncommon and brown tumor has become extremely a rare clinical entity. Hyperparathyroidism is usually associated with high levels of serum calcium. Brown tumor as the only and initial symptom of normocalcemic primary hyp...

non-penetrating head injuries associated with skull base fractures can lead to the development of pneumocephalus upon airs ingress, which leads its course in the subarachnoid space. intracerebral air accumulation is rare and ensuses when a paranasal sinus fracture is associated with a ensues when a paranasal sinus fracture is associated with a nearby parenchymal contusion. a 25-year old man is ...

OBJECTIVES One of the major challenges of cranial base surgery is reconstruction of the dural defect. Following a craniofacial resection, the standard reconstructive technique is direct suture repair of the dural defect with a fascial graft and rotation of an anteriorly based pericranial scalp flap to cover the dura. The introduction of endoscopic techniques and an endonasal approach to the ven...

Objectives The purpose of this study is to experimentally evaluate the use of concentric tube continuum robots in endonasal skull base tumor removal. This new type of surgical robot offers many advantages over existing straight and rigid surgical tools including added dexterity, the ability to scale movements, and the ability to rotate the end effector while leaving the robot fixed in space. In...