Tumour cells may be resistant to radiotherapy that results in unsuccessful cancer treatment in patients. The aim of this study was to evaluate the sensitizing effect of atorvastatin (ATV) on breast cancer (MDA-MB-231) and non-small cell lung cancer (A-549) cells following exposure to ionizing radiation (IR). These cells were treated with ATV and exposed to X-ray at dose 4 Gy. The radiosensitizi...

background: lung cancer is the most common cause of cancer death worldwide with an annual mortality rate of more than 1.3 million worldwide. we aimed to analyze the clinicopathological features of patients with non-small-cell lung cancer (nsclc) in west of iran. methods: 64 patients with nsclc who referred to our clinic were analyzed. sex, age, histopathology, location of the tumor, treatment, ...

Background: Lung carcinoma is a multiple type cancer comprising of small cell and non-small cell carcinomas (NSCLC). For therapeutic and diagnostic purposes, serum monoclonal antibodies have been produced against lung cancer. Objective: To charac-terize a murine monoclonal antibody (ME3D11) reactive with human NSCLC. Methods: A murine monoclonal antibody (ME3D11) reactive with human NSCLC was s...

background the attention of the scientific community has been recently focused on the role of tumor-infiltrating lymphocytes in non-small-cell cancer and there is a convergence of results, supporting a direct proportionality between lymphocytic infiltrate and good prognosis. objectives the aim of our research was to investigate the immune response around and inside the small-cell lung neoplasti...

background: lung carcinoma is a multiple type cancer comprising of small cell and non-small cell carcinomas (nsclc). for therapeutic and diagnostic purposes, serum monoclonal antibodies have been produced against lung cancer. objective: to charac-terize a murine monoclonal antibody (me3d11) reactive with human nsclc. methods: a murine monoclonal antibody (me3d11) reactive with human nsclc was s...

conclusions physicians should be aware of this rare site of metastasis. early diagnosis is of paramount importance in order to effectively prevent the significant morbidity this condition can cause if left untreated. introduction small cell carcinoma constitutes the most aggressive type of lung cancer, with the greatest propensity for early disseminated disease. although commonly neglected due ...

background: the term crystallized silica refers to the crystallized form of sio 2 and quartz, the most frequency composition in the earth’s crust that can cause silicosis and lung cancer through occupational exposure and inhalation of its large quantities. methods: occupational exposure of workers in pakdasht, iran, in 2011 was investigated in four different casting processes in small foundries...

background: mehr-80 is a newly established adherent human large cell lung cancer cell line that has not been transfected until now. this study aims to define the optimal transfection conditions and effects of some critical elements for enhancing gene delivery to this cell line by utilizing different non-viral transfection procedures. methods: in the current study, calcium phosphate (cap), deae-...