The balance between excitatory and inhibitory synaptic inputs, which is governed by multiple synapse organizers, controls neural circuit functions and behaviors. Slit- and Trk-like proteins (Slitrks) are a family of synapse organizers, whose emerging synaptic roles are incompletely understood. Here, we report that Slitrks are enriched in postsynaptic densities in rat brains. Overexpression of S...

The ?-selection checkpoint of T cell development tests whether the has recombined its genomic DNA to produce a functional receptor ? (TCR?). Passage through requires nascent TCR? protein mediate signaling pre-TCR complex. In this study, we show that developing cells at establish an immunological synapse in vitro and situ, resembling mature cell. is dependent on two key pathways known be critica...

Communications [2] Educational Technology Services [3] Finance and Administration [4] First Generation Support Services [5] Graduate and Professional Student Association [6] International Students and Scholars Office [7] Learning Resource Services [8] Office of Career and Professional Development [9] Office of Institutional Research [10] Office of the Registrar [11] Registered Campus Organizati...

Communications [2] Educational Technology Services [3] Finance and Administration [4] First Generation Support Services [5] Graduate and Professional Student Association [6] International Students and Scholars Office [7] Learning Resource Services [8] Office of Career and Professional Development [9] Office of Institutional Research [10] Office of the Registrar [11] Registered Campus Organizati...

Communications [2] Educational Technology Services [3] Finance and Administration [4] First Generation Support Services [5] Graduate and Professional Student Association [6] International Students and Scholars Office [7] Learning Resource Services [8] Office of Career and Professional Development [9] Office of Institutional Research [10] Office of the Registrar [11] Registered Campus Organizati...