The antagonism, by neostigmine, of neuromuscular blockade produced by either Org NC 45 or pancuronium was studied in 29 anaesthetized patients during a continuous infusion of the myoneural blocker. The ED50 of neostigmine (dose which produced a 50% antagonism) when antagonizing Org NC 45 and pancuronium was 0.011 mg kg-1 and 0.010 mg kg-1 respectively. The dose-response relationships for the an...

Materials and methods: In Experiment One, a total of 224 nursery pigs were used in a 28-day trial. Dietary treatments included a control (without ORG or antimicrobial), the control diet containing neomycin and oxytetracycline (154 mg per kg of each; NT), ORG, or both NT and ORG. In Experiment Two, the fi ve dietary treatments included the control, control diet plus NT, and control diet with ORG...

Rapidly reversible, temperature-sensitive (ts) paralytic mutants of Drosophila have been useful in delineating immediate in vivo functions of molecules involved in synaptic transmission. Here we report isolation and characterization of orangi (org), an enhancer of shibire (shi), a ts paralytic mutant in Drosophila dynamin. org is an allele of the stress sensitive B (sesB) locus that encodes a m...

BACKGROUND Home care services in Norway are provided for free, and municipalities are responsible for their provision to all those in need of them, in accordance with the Act on Municipal Health and Care Services. The costs of home care services are increasing. Many municipalities are now working to find the best cost-effective solutions to ensure that home care services are of sufficient quali...

optomotor-blind (omb) and optomotor-blind related-1 (org-1) encode T-domain DNA binding proteins in Drosophila. Members of this family of transcription factors play widely varying roles during early development and organogenesis in both vertebrates and invertebrates. Functional specificity differs in spite of similar DNA binding preferences of all family members. Using a series of domain swap c...

The 19-nor-progestogen norethisterone is used as a progestogen component in contraceptives and in continuous- and sequential combined hormone replacement therapy (HRT) in postmenopausal women. Metabolism of norethisterone in HRT target tissues may play a role in its biological response. The aim of this study was to investigate which steroid-metabolizing enzymes are present in rat uterus, vagina...

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Submicron aerosol physical and chemical properties in remote marine air were measured from aircraft over the Southeast Pacific during VOCALS-REx in 2008 and the North Pacific during IMPEX in 2006, and aboard a ship in the Equatorial Pacific in 2009. A High Resolution – Particle Time of Flight Aerosol Mass Spectrometer (HR-ToFAMS) measured non-refractory submicron aerosol composition during all ...