OBJECTIVE Cryopreservation of immature testicular tissue should be considered as an important factor for fertility preservation in young boys with cancer. The objective of this study is to investigate whether immature testicular tissue of mice can be successfully cryopreserved using a simple vitrification procedure to maintain testicular cell viability, proliferation, and differentiation capaci...

Cryopreservation of testicular tissue might benefit prepubertal boys who must undergo chemotherapy or radiotherapy. Cryopreservation of testicular tissue and testicular cells for intracytoplasmic sperm injection (ICSI) is feasible and widely applied. Testicular tissue from prepubertal boys can also be frozen, by applying techniques used with other tissues and with testicular tissue from adult m...

background & aim: onosma stenosiphon has been used as herbal medicine for healing skin cuts and rashes. however, burn healing effect of this herb has not been yet reported in pharmaceutical texts. the aim of this study was to find out the effect of herb ointment on burn healing the superficial wounds post type ii burns of back and testis region in wistar rats. experimental: a total of 24 r...

Objective- Cryptorchidism, common birth defect of the male genital tract, is one of the causes of fertility problems. The elevation of tissue temperature following of cryptorchidism could induce oxidative stress which influences the cellular and tissue degeneration. Amlodipine is a third-generation of calcium channel blockers which has antioxidant activity. The aim of this stud...

Formalin is widely used in industry and in medicine (as tissue fixative and disinfectant).It contains reactive molecules which have been known for its cytotoxic effects. To evaluate the effect of formalin exposure on the testicular tissue and sperm parameter from neonatal period through physical and sexual maturity, 28 male Wister rats were assigned into two equal test and control groups. The t...

Background: Cyclosporine-A(CsA) is an immunosuppressive polypeptide which is produced byTolypocladium inflatum gams and can cause infertility. Satureja hortensis or summer savory is a one year plant from Lamiaceae family which is used as a motive drug, anti-bloat, anti-infection and sexual power enhancer. According to positive effects of S. hortensis and negative effects of CsA we will evaluate...