Tranquilizer misuse represents a growing international public health problem with heavy social and economic consequences. We aimed to identify the psychosocial determinants of this practice, focusing on modifiable factors including knowledge attitudes towards these medications. A prospective cohort study involving 847 adults accompanying children in primary care clinics was carried out Spain. v...

In a variety of cellular and subcellular preparations, total ATP-hydrolyzing activity was potently inhibited by tricyclic antidepressants (TA) and phenothiazine tranquilizers (PT) . In leukocytes, prein~ubation of the cells with 5 x 10 M TA and 1 x 10M PT resulted in up to 878 and 948 inhibition of the ATPase activity . Among TA, dibenzocycloheptadienes were somewhat more potent inhibitors than...

INTRODUCTION There are many common drugs which have significant sedative-hypnotic properties. Alcohol and barbiturates have been discussed separately in this appendix, and their many pharmacological similarities were indicated. Barbiturates are often considered the prototype of sedative-hypnotic drugs; pharmacologically related compounds are frequently identified or discussed in terms of their ...

Based on these approaches, several types of medications, such as taste adulterants, stimulants, and tranquilizers have been tested as aids to smoking cessation (Kozlowski, in press; Raw 1978; Grabowski and Hall, this volume). Most of these medications have not been efficacious. Nicotine chewing gum is the exception (Hughes and Miller 1984). The major hypotheses to explain the efficacy of nicoti...

The present epidemiological survey was carried out to estimate the prevalence and pattern of drug abuse in urban population of Madhya Pradesh because such studies were lacking from this state. In the population of 5326, we found that 38.6% were current users. In order of frequency, the drugs used were - tobacco (36.8%), alcohol (26.5%), painkillers (9.8%), cannabis (4.1%), tranquilizers (2.4%) ...

Herbal medicines have great demand in the treatment of various kinds illness. Ayurvedic system medicine has consisted many herbal sources which ashwagandha one them are very popular sources. Many literature surveys suggest that is used as an immunomodulator, tranquilizer, antioxidant, antidiabetic, and nootropic activity. Present research work explored potential benefit by designing suitable gr...

INTRODUCTION There are many common drugs which have significant sedative-hypnotic properties. Alcohol and barbiturates have been discussed separately in this appendix, and their many pharmacological similarities were indicated. Barbiturates are often considered the prototype of sedative-hypnotic drugs; pharmacologically related compounds are frequently identified or discussed in terms of their ...

Serum lipids and Jipoprotein levels were determined in 35 schizophrenics treated with Phenothiazine, 30 with butyrophenone and 22 with both drugs for six to twelve months. Total cholesterol, VLD L — cholesterol and LDL cholesterol levels were significantly elevated in patients on phenothiazine and LDL cholesterol in patients on butyrophenone. VLD L and LD L — cholesterol levels were significant...