نتایج جستجو برای: transforming growth factor alpha

تعداد نتایج: 1625422  

Journal: :Biology of reproduction 2000
V Doraiswamy J A Parrott M K Skinner

Greater than 95% of ovarian cancers originate in the epithelial cells on the surface of the ovary. The current study investigates the expression and action of transforming growth factor alpha (TGFalpha) in ovarian surface epithelium (OSE) and the underlying stroma in both normal and tumorigenic ovarian tissues. Normal bovine ovaries are used in the current study as a model system to investigate...

2007
Anna-Lotta Hallbeck M. D

.................................................................................... 5 ABBREVIATIONS .......................................................................... 7 FOREWORD ................................................................................... 9 INTRODUCTION .......................................................................... 10 GENERAL ASPECTS ON GROWTH REGULAT...

Background and Objectives: Different diets have important roles in human health and aging. In the current study, we aimed to characterize the Klotho, an anti-aging protein, gene expression and protein level in the serum and assess the protein levels of Transforming growth factor-β and Platelet-derived growth factor in old rats which treated with different diets (high-fat, high-protein, low calo...

Journal: :The Journal of Cell Biology 1985
J Massagué

The epidermal growth factor (EGF) receptor mediates the induction of a transformed phenotype in normal rat kidney (NRK) cells by transforming growth factors (TGFs). The ability of EGF and its analogue TGF-alpha to induce the transformed phenotype in NRK cells is greatly potentiated by TGF-beta, a polypeptide that does not interact directly with binding sites for EGF or TGF-alpha. Our evidence i...

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