BACKGROUND Vitamin D (Vit D) is important for the regulation of reproductive physiology. In humans, maternal Vit D deficiency has been implicated in several reproductive- and pregnancy-related disorders. Very few data are available regarding the Vit D status in male partners of couples attempting pregnancy. This observational study (IRB Prot. N. 078/13) aimed to evaluate whether low Vit D serum...

Several previous reports of small cohorts have found significantly higher serum 1,25-dihydroxy vitamin D (1,25-vit D) in obese compared with nonobese whites. Based on these reports and on recent in vitro studies of adipocytes which suggest that administration of 1,25-vit D can stimulate lipogenesis and inhibit lipolysis, some investigators have proposed that high 1,25-vit D may play a role in p...

Background: Vitamin D (Vit D) is linked to various conditions including musculoskeletal, metabolic and   cardiopulmonary diseases. However, it is not clear whether correction of vit D deficiency exerts any beneficial effect in patients with pulmonary hypertension. Methods: This study was a prospective uncontrolled longitudinal study. Patients with pulmonary hypertension and vit D d...

Vitamin D (VIT D) deficiency is determined by serum 25-OH-D. Several studies revealed high prevalence of VIT D deficiency in females of the Asian sunny countries. 162 females referred to Urmia Orthopedic Clinics, with bone and muscle pain with the ages 15 up to 40 yrs participated in the study. The individuals were not pregnant, lactating, with no systemic or neurological diseases during the co...

Low vitamin D is involved in allergic asthma and rhinitis. IL-31 and IL-33 correlate with Th2-associated cytokines in allergic disease. We investigated whether low vitamin D is linked with circulating IL-31 and IL-33 in children with allergic disease of the airways. 25-Hydroxyvitamin D [25(OH) Vit D], IL-31, and IL-33 plasma levels were measured in 28 controls (HC), 11 allergic rhinitis (AR) pa...

Background and Objective: Vitamin D (Vit D) has an important role as immunoregulator. Its deficiency is deemed as a risk factor for respiratory system infection. In this study the serum Vit D levels of healthy and with pneumonia children were compared. Methods: In this prospective case control study, 31 hospitalized children due to pneumonia and 40 healthy children both aged between 6 a...

BACKGROUND Vitamin D (Vit D) is linked to various conditions including musculoskeletal, metabolic and cardiopulmonary diseases. However, it is not clear whether correction of vit D deficiency exerts any beneficial effect in patients with pulmonary hypertension. METHODS This study was a prospective uncontrolled longitudinal study. Patients with pulmonary hypertension and vit D deficiency were ...

OBJECTIVE To determine whether maternal vitamin D supplementation, in the vitamin D deficient mother, prevents neonatal vitamin D deficiency. DESIGN Open-label randomized controlled trial. SETTING Metropolitan Melbourne, Australia, tertiary hospital routine antenatal outpatient clinic. PARTICIPANTS Seventy-eight women with singleton pregnancies with vitamin D deficiency/insufficiency (ser...

OBJECTIVES To assess zinc (Zn) and vitamin D (Vit. D) status in chronic Hepatitis C virus- (HCV) infected patients and their relationship to interleukin- (IL-) 17 and disease severity and then investigate whether Zn and Vit. D3 modulate IL-17 expression in chronic HCV patients. METHODS Seventy patients and fifty healthy subjects were investigated. Serum levels of Zn, Vit. D, and IL-17 were as...

We read with great interest the article of Bayani et al. on the “Vitamin-D status in diabetic patients” published in Caspian Journal of Internal Medicine (CJIM) (1). Bayani et al. provided a timely and useful summary of the status of vitamin D (vit D) deficiency in type 2 diabetes mellitus. They reported some interesting results based mostly on statistical associations that vit D concentration ...