Rheumatoid arthritis (RA) is an autoimmune disease that is characterized by chronic inflammation affecting target tissues including the joints, bones, and synovial membrane. However, the etiology and pathogenesis of RA remains to be determined, and investigations into the treatment of RA are imperative. Vitamin D (Vit D) was previously found to be associated with the activity of RA and exerts t...

UV radiation is a well-documented human carcinogen, indisputably linked to the current continued increased rate of skin cancer. UV radiation is also responsible for cutaneous synthesis of vitamin (vit) D3, a substance that is then sequentially hydroxylated in the liver and kidney to yield 1,25(OH)2 vit D, a hormone critical for calcium homeostasis and skeletal maintenance. Because the UV action...

The purpose of this study was to investigate the effects of vitamin B6 (Vit B6) on oxidant and antioxidant status in streptozotocin-induced diabetic rats. Thirty-two Wistar rats were divided into four groups: control (C), control + Vit B6 group (C + Vit B6), diabetes (D), and diabetes + Vit B6 group (D + Vit B6). Vit B6 (4 mg/kg body weight) was administered in drinking water for 4 weeks after ...

Vitamin D (Vit D) plays multiple roles in bodily functions. Vit D deficiency is a common, but often under-diagnosed condition with possible serious complications. According to some research, Vit D is important particularly among women and children. No data were found concerning the Vit D status among urban Bedouin women of childbearing age. The research study is retrospective and descriptive. W...

introduction vit d level is low in human milk (20-60 iu/lit) thus dialy supplement of 400 vit d is advised since birth for all infants. on the other hand upper limit dose for long term vit d intake is 1000 iu/day for children less than one year of age. excessive vit d more than upper limit by physicians or parents can cause hypervitaminosed. we report a rare case of hypervitaminose d in two mon...

background and objective: vitamin d (vit d) has an important role as immunoregulator. its deficiency is deemed as a risk factor for respiratory system infection. in this study the serum vit d levels of healthy and with pneumonia children were compared. methods: in this prospective case control study, 31 hospitalized children due to pneumonia and 40 healthy children both aged between 6 and 60 mo...

pth is the most important factor which control calcium homeostasis in the body in this study we tried to determine the normal range of pth and vitamin d with examining the relation between pth and bone density and vitamin d on the base of bones biological changes. our subjects were, 20 to 69 years-old men and women of tehran. serum volume of pth and vitamin d in different decades of life had si...

Purpose Here, we studied the beneficial effects of aerobic exercise on metabolic syndrome components, cognitive performance, brain derived neurotrophic factor (BDNF) and irisin in ovariectomized rats with different serum vitamin D (Vit D) status. Methods Eighty female wistar rats were divided into 2 groups of sham operated (sham, n = 8), and ovariectomized (OVX, n = 72). Then OVX were divided...

Vitamin D (vit D) is not only contributed to maintaining normal calcium metabolism, but also is crucial for an extensive range of non-classic actions. The antioxidant effect of vit D is between the newest suggested non-calcemic roles of this compound. According to the vit D deficiency could be related to several chronic diseases such as diabetes, cardiovascular disease and chronic kidney diseas...