Hyperosmolar solutions and digital massage are frequent adjuncts employed to minimize vitreous loss at cataract extraction (Scott, i962; Virno, Cantore, Bietti, and Bucci, I963; Murray and Tipler, I966; Guyton, I954; Kirsch and Steinman, I955). The former is effective in reducing vitreous mass during the time interval usually necessary to complete a lens extraction, but the latter may not have ...

An 80-year-old man had intraoperative loss of an intraocular lens (IOL) in the vitreous and simultaneous implantation of an anterior chamber lens. For the first 3 years his course was uncomplicated, but after this time he noted monocular double vision. The IOL in the vitreous had moved into the optic axis of the eye. The case presented here underlines the possibility of complications occurring ...

This paper describes a simplified technique for biopsy of the retina and choroid which had been used in 5 human volunteers. The biopsy was carried out in 4 immediately before enucleation of an eye for malignant melanoma and in 1 patient who was undergoing trabeculectomy for painful glaucoma associated with retinitis pigmentosa. A combination of intravenous mannitol and transient controlled syst...

PURPOSE To determine whether aging vitreous collagen fibrils undergo ultrastructural changes that might underlie vitreous liquefaction and posterior vitreous detachment. METHODS Vitreous collagen fibrils from 21 human subjects (age range, 3-89 years) and from bovine eyes were isolated on electron microscopy grids. Cupromeronic blue labeling in the presence of 0.3 M MgCl(2) and immunogold labe...

Multiple rheological studies have characterized the dynamic material properties of adult vitreous, but no studies have investigated vitreous properties in the immature eye. In this study, premature, infant and adult ovine vitreous specimens were tested in shear to identify differences in dynamic moduli with age. Significant inertial artifact and rapid degradation of the vitreous ex vivo hindere...

Although rare, ocular reticulum cell sarcoma presents a recognisable clinical pattern, as confirmed by 3 new cases. Typical patients, in their sixth and seventh decades, initially complain of gradual visual loss. Examination reveals 'uveitis' with prominent vitreous debris and/or chorioretinal infiltrative lesions. Topical steroid and mydriatic therapy is ineffective. Reticulum cell sarcoma in ...

PURPOSE Results from this and other laboratories strongly suggest that differences in the properties of the ocular media that bathe cells in the anterior and posterior regions of the lens contribute to its normal growth patterns and polarity. The aim of this study was to compare the effects of aqueous and vitreous on the morphology of lens epithelial explants, with particular attention to chang...

Severe loss of visual acuity due to vitreous opacities may result from haemorrhages, inflammatory and degenerative conditions, tumour cells, or amyloidthe last being rare (Duke-Elder, I969; Jaffe, I969). It is important, however, to recognize amyloid disease as being a cause of vitreous opacities, because most previously reported cases have been patients with familial amyloidosis, a systemic di...

The purpose of this study was to describe a presumed case of Epstein-Barr virus (EBV)-associated retinal vasculitis in a 42-year-old female with sudden unilateral vision loss and successful treatment with acyclovir therapy. Diagnostic vitreous biopsy of the right eye was performed to test for EBV and other known infectious causes of retinitis and evaluate vitreous cells and serological testing....