نتایج جستجو برای: vntr analysis
تعداد نتایج: 2825093 فیلتر نتایج به سال:
there are conflicting results concerning dc-sign and dc-signr vntr polymorphisms. the present study aimed to evaluate the possible association between dc-sign as well as dc-signr vntr polymorphisms and pulmonary tuberculosis (ptb) in a sample of iranian population. this case-control study was done on 171 ptb and 161 healthy subjects. the variants were detected by polymerase chain reaction (pcr)...
A multiplex PCR method incorporating primers flanking three variable-number tandem repeat (VNTR) loci (arbitrarily labeled TR1, TR2, and TR3) in the CT18 strain of Salmonella enterica serovar Typhi has been developed for molecular typing of S. enterica serovar Typhi clinical isolates from several Asian countries, including Singapore, Indonesia, India, Bangladesh, Malaysia, and Nepal. We have de...
QUB11a is used as a locus for variable number of tandem repeats (VNTR) analysis of Mycobacterium tuberculosis Beijing lineage. However, amplification of QUB11a occasionally produces large fragments (>1,400 bp) that are not easily measured by capillary electrophoresis because of a lack of the typical stutter peak patterns that are used for counting repeat numbers. IS6110 insertion may complicate...
ایران کشوری در جنوب غربی آسیا است که در منطقه خاورمیانه قرار دارد. جمعیت ایران از اقوام زیادی از جمله: فارس، آذری، کرد، لر، بختیاری، بلوچ، مازندرانی، گیلک، قشقایی، عرب، لک، تالشی، ترکمن، خلج، آشوری، کلدانی، مندایی(صائبی)، تات، گرجی، سیستانی، ارمنی، و یهودی تشکیل شده است. در این مطالعه 697 نفر از سه جمعیت آذری تبریز ( شامل287 مرد و 10 زن)، لر یاسوج ( 191 مرد و 9 زن) و ابرکوه یزد (100 مرد و 100 ز...
The variable number of tandem repeat (VNTR) of thymidylate synthase (TS) gene, mainly 2 repeat (2R) and 3 repeat (3R), is one of the genetic variations that can potentially predict the effectiveness of 5-fluorouracil-based chemotherapy. In this study we identified an additional single nucleotide polymorphism (SNP) in the VNTR of TS, followed by functional and clinical analysis of the SNP. Two-h...
The population structure of the species Legionella pneumophila was investigated by multilocus variable number of tandem repeats (VNTR) analysis (MLVA) and sequencing of three VNTRs (Lpms01, Lpms04 and Lpms13) in selected strains. Of 150 isolates of diverse origins, 136 (86 %) were distributed into eight large MLVA clonal complexes (VACCs) and the rest were either unique or formed small clusters...
5-Fluorouracil (5FU), a widely used chemotherapeutic drug, inhibits the DNA replicative enzyme, thymidylate synthase (Tyms). Prior studies implicated a VNTR (variable numbers of tandem repeats) polymorphism in the 5'-untranslated region (5'-UTR) of the TYMS gene as a determinant of Tyms expression in tumors and normal tissues and proposed that these VNTR genotypes could help decide fluoropyrimi...
BACKGROUND Tuberculosis (TB) is a serious problem in China. While there have been some studies on the nationwide genotyping of Mycobacterium tuberculosis (M. tuberculosis), there has been little detailed research in Beijing, the capital of China, which has a huge population. Here, M. tuberculosis clinical strains collected in Beijing during 2009 were genotyped by classical methods. METHODOLOG...
Francisella tularensis, the etiological agent of tularemia, is found throughout the Northern hemisphere. After analyzing the F. tularensis genomic sequence for potential variable-number tandem repeats (VNTRs), we developed a multilocus VNTR analysis (MLVA) typing system for this pathogen. Variation was detected at six VNTR loci in a set of 56 isolates from California, Oklahoma, Arizona, and Ore...
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