نتایج جستجو برای: xanthene derivatives

تعداد نتایج: 105289  

2014
Yonghoon Kwon Parkyong Song Jong Hyuk Yoon Jaewang Ghim Dayea Kim Byungjun Kang Taehoon G. Lee Jin-Ah Kim Joong-Kwon Choi In Kwon Youn Hyeon-Kyu Lee Sung Ho Ryu Thierry Alquier

5' AMP-activated protein kinase (AMPK) is a highly conserved serine-threonine kinase that regulates energy expenditure by activating catabolic metabolism and suppressing anabolic pathways to increase cellular energy levels. Therefore AMPK activators are considered to be drug targets for treatment of metabolic diseases such as diabetes mellitus. To identify novel AMPK activators, we screened xan...

Farhad Shirini, Gholam Hossein Imanzadeh Masoumeh Abedini Parisa Ghods Ghasemabadi

1,3-Dibromo-5,5-dimethylhydantoin (DBH), as a cheap and commercially available reagent, is efficiently able to catalyze the synthesis of polyhydroquinoline derivatives and 12-aryl-8,9,10,12-tetrahydro[a] xanthene-11-ones via one-pot multi-component reactions. This novel synthetic method has the advantages of low cost and availability of the catalyst, short reaction times, high to excellent yiel...

2010
Noorhafizah Hasanudin Aisyah Saad Abdul Rahim Salizawati Muhamad Salhimi Jia Hao Goh Hoong-Kun Fun

The main mol-ecule of the title compound, C(2)H(8)N(+)·C(25)H(31)O(5) (-)·C(25)H(32)O(5)·0.5C(6)H(14)·H(2)O, exists as two crystallographically independent mol-ecules, the hydr-oxy group of one being deprotonated. The pyran rings of both independent units adopt boat conformations. One of the two cyclo-hexene rings of the xanthene unit adopts an envelope conformation whereas the other is in a ha...

Journal: :Chemical and Pharmaceutical Bulletin 1989

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