Asymmetric cell division is utilized by a broad range of cell types to generate two daughter cells with distinct cell fates. In stem cell populations asymmetric cell division is believed to be crucial for maintaining tissue homeostasis, failure of which can lead to tissue degeneration or hyperplasia/tumorigenesis. Asymmetric cell divisions also underlie cell fate diversification during developm...

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One of the most exciting areas in lithium ion batteries is engineering structured silicon anodes. These new materials promise to lead the next generation of batteries with significantly higher reversible charge capacity than current technologies. One drawback of these materials is that their production involves costly processing steps, limiting their application in commercial lithium ion batter...

69 INTRODUCTION The success of operating a drive-thru facility depends on queues and waiting times experienced by customers. Drivethru facilities are required to provide queuing areas that can hold the expected maximum queue length. Rates of arrivals and service times affect the required queuing areas for drive-thru facilities. Gattis recommended queuing areas for drive-thru facilities located ...

Previous studies identified a family of organic anion transport proteins (OATPs), many of which have C-terminal PDZ binding consensus sequences. In particular, the C-terminal four amino acids of Oatp1a1, a transporter on rat and mouse hepatocytes, comprise a consensus binding site for PDZK1. In PDZK1 knockout mice and in transfected cells where PDZK1 expression was knocked down, Oatp1a1 accumul...

Acute otitis media, inflammation of the middle ear, is the most common bacterial infection in children and, as a consequence, is the most common reason for antimicrobial prescription to this age group. There is currently no effective vaccine for the principal pathogen involved, non-typeable Haemophilus influenzae (NTHi). The most frequently used and widely accepted experimental animal model of ...

implant and DMPA appears increasingly important in light of one recent animal study suggesting a relationship between progestin exposure and vaginal atrophy (which might lead to increased risk of HIV infection).6 Although it is premature to extrapolate the findings of this study to humans, the results highlight the importance of correct and consistent condom use among users of hormonal contrace...