Importance The true prevalence of hidradenitis suppurativa (HS) is unknown. Objective To establish standardized overall and group-specific prevalence estimates for HS in the United States. Design, Setting, and Participants This retrospective analysis included a demographically heterogeneous population-based sample of more than 48 million unique patients across all US census regions. As of O...

Abstract. The signal of magnetic resonance imaging (MRI) can be enhanced by several orders magnitude using hyperpolarization. In comparison to a broadly used dynamic nuclear polarization (DNP) technique that is already in clinical trials, the parahydrogen (pH2)-based hyperpolarization approaches are less cost-intensive, scalable, and offer high throughput. However, pH2 generator necessary. Avai...

A variety of interventions have proven effective in reducing the risk of a first stroke.1 Nevertheless, each year, more than 700 000 Americans have strokes and more than 150 000 die, making stroke the country’s third-leading cause of death.2 More than 25% of stroke survivors older than age 65 years are disabled 6 months later.2 On the basis of the results of prospective randomized clinical tria...

© 2011. The Authors. Licensee: OpenJournals Publishing. This work is licensed under the Creative Commons Attribution License. Background: Tuberculosis (TB) remains one of the top public health problems in South Africa. Approximately 150 000 new cases and 10 000 TB-related deaths are reported in South Africa annually. In declaring TB a global emergency in 1993, the World Health Organization deve...

The 6dF Galaxy Survey is measuring around 150 000 redshifts and 15 000 peculiar velocities from galaxies over the southern sky at | b | > 10◦. When complete, it will be the largest survey of its kind by more than an order of magnitude. Here we describe the characteristics of the Second Incremental Data Release (DR2) and provide an update of the survey. This follows earlier data made public in D...

60 infants with neonatal tetanus were treated at random either by 40 000 units of equine tetanus antitoxin (TAT), intravenously and intramuscularly, or by 40 000 units TAT, IV and IM, plus 150 units of human tetanus immune globulin TIG) intrathecally. There were 30 infants in each treatment group. Babies were similar in age, sex, weight, incubation period, temperature, and signs and symptoms on...

The membrane-bound NADH dehydrogenase (E.C. 1.6.99.3) has been solubilized by sodium deoxycholate treatment of membranes and purified 75 fold by column chromatography on Sephadex G-150 and DEAE cellulose in the presence of sodium cholate. The native enzyme has an apparent molecular mass (M r) of 97 000, containing polypeptides of Mr of about 15 000. The pH optimum was at 7.5. The enzyme was spe...

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The study of patients with inherited bleeding problems is a powerful approach in determining the function and regulation of important proteins in human platelets and their precursor, the megakaryocyte. The normal range of platelet counts in the bloodstream ranges from 150 000 to 400 000 platelets per microliter and is normally maintained within a narrow range for each individual. This requires ...