OBJECTIVE To evaluate the effect of dexamethasone administration on labor duration. METHOD In this controlled trial 122 nulliparous women with a full-term pregnancy and a Bishop score of 7 or greater were randomly assigned to receive a single 8-mg dose of dexamethasone or placebo 6 hours before initiation of labor induction. RESULTS The interval between initiation of labor induction and beg...

blocking antibodies are valuable tools for inhibiting the specific receptor- ligand interactions. the interaction of co-stimulatory molecules on the antigen presenting cells with their ligands on t cells is an essential step for t cell activation. in the present study, the effect of blocking antibody against cd40 on its t cell stimulatory potential is investigated. the dcs (dendritic cells) wer...

Phages 933W, BAA2326, 434, and λ are evolutionarily-related temperate lambdoid phages that infect Escherichia coli. Although these are highly-similar phages, BAA2326 and 933W naturally encode Shiga toxin 2 (Stx⁺), but phage 434 and λ do not (Stx(-)). Previous reports suggest that the 933W Stx⁺ prophage forms less stable lysogens in E. coli than does the Stx(-) prophages λ, P22, and 434. The hig...

BACKGROUND Finding an effective, non-pharmacological approach to treat opioid withdrawal could remove some of the barriers associated with pharmacotherapy. The BRIDGE® is a noninvasive, percutaneous electrical nerve field stimulator developed to target pain. OBJECTIVES This pilot study aimed to determine (1) the effects of the BRIDGE on withdrawal scores during the induction phase of opioid w...

Abstract: Piperidine alkaloids are members of the alkaloid family that is characterized by presence a six-membered nitrogen-containing heterocycle. found mainly in plants and often exhibit interesting biological pharmacological activities. Despite accumulation these natural products plants, relatively low quantities produced absolute terms thus synthesis derivatives thereof remains relevant to ...

trinitrobenzene sulfonic acid (tnbs)-induced colitis is one of the most common methods for studying inflammatory bowel disease in animal models. several factors may, however, affect its reproducibility, rate of animal mortality, and macroscopic and histopathological outcomes. our aim was to validate the main contributing factors to this method and compare the effects of different reference drug...

context : cumin ( cuminum cyminum l.) as a member of the apiaceae family is one of the most important medicinal plants in the world. objective : an experiment was conducted for evaluation of callus induction optimization in cumin accessions (shahdad, koohbanan, badrood and afghanistan). materials and methods : factorial experiment based on completely randomized design (crd) with three replicati...