BACKGROUND Previous studies have observed that exercise-induced bronchoconstriction (EIB) is more common and more strongly related to exercise related breathing problems in female adolescents than male adolescents. However, few studies have investigated the association between EIB and health related quality of life (HRQoL) from a gender perspective. The aim of this study was to examine the asso...

We have demonstrated that the isoflavone, genistein, stimulates growth of estrogen-dependent human breast cancer (MCF-7) cells in vivo (C. Y. Hsieh et al., Cancer Res., 58: 3833–3838, 1998). The isoflavones are a group of phytoestrogens that are present in high concentrations in soy. Whether consumption of genistein from soy protein will have similar effects on estrogen-dependent tumor growth a...

Recently, it was found by Schneider et al. [Proc. Natl. Acad. Sci. USA 108, 3838 (2011)], using simulations, that scale-free networks with "onion structure" are very robust against targeted high degree attacks. The onion structure is a network where nodes with almost the same degree are connected. Motivated by this work, we propose and analyze, based on analytical considerations, an onionlike c...

The goal of the study was to improve the methodology of HIV genotyping for analysis of HIV drug resistance and HIV clustering. Using the protocol of Gall et al. (A. Gall, B. Ferns, C. Morris, S. Watson, M. Cotten, M. Robinson, N. Berry, D. Pillay, and P. Kellam, J Clin Microbiol 50:3838-3844, 2012, doi:10.1128/JCM.01516-12), we developed a robust methodology for amplification of two large fragm...

Systems with large amounts of computing power and storage are required to simulate very large neural networks capable of tackling complex control problems and real-time emulation of the human sensory, language and reasoning systems. General-purpose parallel computers do not have communications, processor and memory architectures optimized for neural computation and so can not perform such simul...

Ancient retroposon insertions can be used as virtually homoplasy-free markers to reconstruct the phylogenetic history of species. Inherited, orthologous insertions in related species offer reliable signals of a common origin of the given species. One prerequisite for such a phylogenetically informative insertion is that the inserted element was fixed in the ancestral population before speciatio...

Correspondence: Junichi Yoshida Infection Control Committee, Shimonoseki City Hospital, 1-13-1 Koyo-cho, Shimonoseki 750-8520, Japan Tel +81 83 231 4111 Fax +81 83 224 3838 Email [email protected] Abstract: It is not known whether or not ward-specific antimicrobial use density (AUD) affects the ratio of methicillin-resistant Staphylococcus aureus (MRSA) in culture-positive S. aureus. A 60-...

Amale neonateweighing 3838 g was born at 39weeks of gestation by elective cesarean delivery due to breech presentation. The umbilical cord was clamped by the surgeon approximately 20 cm from the umbilical base and the neonate was transferred to the midwife for final clamping. The cord was clamped again at approximately 3 cm from the umbilical base. The residual umbilical cord was approximately ...