We study residuals of parametric accelerated failure time (AFT) models for censored data, with the main aim of inferring the correct functional form of possibly misspecified covariates. We demonstrate the use of the methods by a simulated example and by applications to two reliability data sets. We also consider briefly a corresponding approach for parametric proportional hazards models.

In this article we develop an Instrumental Variable estimation procedure that corrects for possible endogeneity of a variable in a duration model. We assume a Generalized Accelerated Failure Time (GAFT) model. This model is based on transforming the durations and assuming a distribution for these transformed durations. The GAFT model encompasses two competing approaches to duration data; the (M...

Background: Study in design to incorporate accelerated proliferation correction factors into linearquadratic and multiple-component models. Materials and Methods: Accelerated proliferation rate correction factor has been incorporated into the linearquadratic and the multiple component models by applying accelerated exponential cell growth to explain the tumor cell kinetics and estimates proper ...

Kendall and Gehan estimating functions are used to estimate the regression parameter in accelerated failure time (AFT) model with censored observations. The accelerated failure time model is the preferred survival analysis method because it maintains a consistent association between the covariate and the survival time. The jackknife empirical likelihood method is used because it overcomes compu...

usually, in monitoring schemes the nominal value of the process parameter is assumed known. however, this assumption is violated owing to costly sampling and lack of data particularly in healthcare systems. on the other hand, applying a fixed control limit for the risk-adjusted bernoulli chart causes to a variable in-control average run length performance for patient populations with dissimilar...

Abstract The mean residual life function (mrlf) of a subject is defined as the expected remaining lifetime of the subject given that the subject has survived up to a given time. The commonly used regression models as proportional mean residual life (PMRL) and linear mean residual life (LMRL) have limited applications due to adhoc restriction on the parameter space. The regression model we propo...

The biological effect of alkaline water consumption is object of controversy. The present paper presents a 3-year survival study on a population of 150 mice, and the data were analyzed with accelerated failure time (AFT) model. Starting from the second year of life, nonparametric survival plots suggest that mice watered with alkaline water showed a better survival than control mice. Interesting...

Accelerated failure time (AFT) model is commonly applied in engineering studies to address the failure rate of a machine. In humans, survival profile of transplant patients is among the rare scenarios whereby AFT is applicable. To date, it is uncertain whether reliable risk estimates and age-specific mortality trajectories have been published using conventional statistics approach. By investiga...

BACKGROUND The aim of this study is to evaluate the prognostic factors of overall survival (OS) after haematopoietic stem cell transplant (HSCT) in acute lymphoblastic leukaemia (ALL) patients using accelerated failure time (AFT), Cox proportional hazard (PH), and Cox time-varying coefficient models. METHODS 206 patients were enrolled after HSCH in Shariati Hospital between 1993 and 2007. The...