background: adipose derived stem cells (ascs) provoke the accumulation and expansion of regulatory t cells, leading to the modulation of immune responses in tumor microenvironment. objective: to assess the effect of tumoral ascs on the trend of regulatory t cells differentiation. methods: peripheral blood naïve cd4+ t cells were co-cultured with ascs derived from breast cancer or normal breast ...

background: the aim of this research was to evaluate the effect of adipose derived stem cells on bone repair in through and through mandibular bone defects of canine. materials and methods: in this prospective comparative study, adipose-derived stem cells were isolated from subcutaneous fat of lateral thoracic area of 4 dogs. the isolated cells were cultured and expanded through 3 passages. the...

Tendon never restores the complete biological and mechanical properties after healing. Bone marrow and recently adipose tissue have been used as the sources of mesenchymal stem cells, which have been proven to enhance tendon healing. Stromal vascular fraction (SVF), derived from adipose tissue by an enzymatic digestion, represents an alternative source of multipotent cells, which undergo differ...

Arm grooves of star-fish have mesenchymal stem cells derived from adipose tissue cell. Widespread studies have shown that stem cells derived from adipose-derived mesenchymal stem cell from bone marrow have many similarities in terms of the ability to differentiate into a variety of tissues. Most of the animals live in warm and shallow waters and the waters of this feature is that it is low in d...

Background: Preeclampsia is one of the most common complications of pregnancy that occurs after the 20th weeks of pregnancy.The pathophysiology of this disease is not exactly known. Transforming Growth Factor-beta (TGF-β) and Nitric Oxide (NO) are thekey regulatory factors secreted by Mesenchymal stem Cells (MSCs). Objectives: The aim of the present study was to evaluate the TGF-β and NO secret...

background: in recent years, adipose tissue, due to the stem cells contained within, has found a new special place in laboratory and clinical applications. these adipose‑derived stem cells (adscs) have the same characteristics of bone marrow mesenchymal stem cells (bmscs). although bone marrow (bm) is not easily accessible and its procurements may be painful, most patients possess excess fat wh...

the biological interaction between the jaw bones and dental implant is fundamental for the long-term success of dental implant placement. nevertheless, the insufficient bone volume remains a major clinical problem, especially in case of immediate dental implant. using a canine model, the present study proves the regenerative potential of adipose- derived stem cells (adscs) to repair peri-implan...

according to significant improvements in the tissue engineering field over the past several years, lung tissue cells have recently attracted more attention due to the high prevalence and diversity in related diseases. however, selection of an appropriate cell type, screening of suitable conditions for growth and proliferation, as well as subsequent implantation into the body to repair and regen...