نتایج جستجو برای: aflatoxin processing stage

تعداد نتایج: 842458  

2005
Carla Mendonça Armando Venâncio

Aflatoxin M1 (AFM1) is an important mycotoxin frequently found in milk and in dairy products. It is a minor metabolic product of Aspergillus flavus and A parasiticus. However, it occurs in dairy products as a metabolite formed in cows from aflatoxin B1 contained in animal feeds. In cheese production, AFM1 distributes between curd and whey, being present in products derived from cheese whey proc...

Background: Due to their high amount of carbohydrate and enough moisture, cereals are a good environment for the growth of toxigenic fungi. Because of the carcinogenicity and mutagenicity of mycotoxins, preventing them from entering the food chain is essential. Therefore, the present study was conducted to determine the amount and type of contaminated imported cereals and rice produced in Khuze...

Journal: :journal of agricultural science and technology 2010
h. mohammadi m. alizadeh m. r. bari a. khosrowshahi h. tajik

a model capable of predicting the minimum content of aflatoxin m1 (afm1) in iranian while brine cheese has been developed using a chemometric approach to determine the optimum processing conditions. renneting temperature, cut size, stirring time, press time, curd size and saturated brine ph were all regarded as process variables. three-dimensional response surface and contour plots were drawn. ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1984
J D Groopman L J Trudel P R Donahue A Marshak-Rothstein G N Wogan

Monoclonal antibodies specific for aflatoxin B1, aflatoxin B2, aflatoxin M1, and the major aflatoxin-DNA adducts were obtained following fusion of mouse SP-2 myeloma cells with spleen cells of mice immunized with aflatoxin B1 covalently bound to bovine gamma globulin. The aflatoxin-modified protein used to immunize mice was produced chemically by activating aflatoxin B1 to a 2,3-epoxide derivat...

Journal: :Journal of food protection 2016
Samuel M C Njoroge Limbikani Matumba Kennedy Kanenga Moses Siambi Farid Waliyar Joseph Maruwo Emmanuel S Monyo

A 3-year comprehensive analysis of aflatoxin contamination in peanut butter was conducted in Zambia, sub-Saharan Africa. The study analyzed 954 containers of 24 local and imported peanut butter brands collected from shops in Chipata, Mambwe, Petauke, Katete, and Nyimba districts and also in Lusaka from 2012 to 2014. For analysis, a sample included six containers of a single brand, from the same...

Journal: :The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2009
Dilşa Mizrak Başak Engin Fatih Oğuz Onder Burcu Yener Mehmet Bektaş Zeynep Biyikli Ramazan Idilman Kubilay Cinar Kaan Karayalçin Sadik Ersöz Selim Karayalçin Ali Ozden Cihan Yurdaydin Nuray Yazihan Haluk Ataoğlu Hakan Bozkaya Ozden Uzunalimoğlu

BACKGROUND/AIMS Hepatocellular carcinoma is the fifth most common cancer and a major public health problem worldwide. Differences in distribution of hepatocellular carcinoma incidence are probably due to different levels of exposure to hepatocellular carcinoma risk factors: chronic infections with hepatitis B virus (HBV) and aflatoxin exposure in developing countries, and smoking and alcohol ab...

2006
John D. Groopman Julia A. Hasler Laura J. Trudel Anthony Pikul Paul R. Donahue Gerald N. Wogan

The development of molecular dosimetry methods will simplify the identification of people at high risk for cancer. A combined monoclonal antibody ¡mmunoaffinitychromatography/high performance liquid chromatography method has been devised to isolate and quantify aflatoxinDNA adducts and other metabolites in rat urine samples. We report the production of 11 different monoclonal antibodies recogn...

2006
David A. Schwartz

AFLATOXIN B1, a carcinogenic metabolite of the fungus Aspergillus flavus, is acutely toxic to a number of species, including rats. Male rats (LD50 7-2 mg./kg.) are more susceptible to the acute oral effects of aflatoxin than are females (LD50 17.9 mg./kg.) (Butler, 1964). Aflatoxin B1 is metabolised to aflatoxin M1 which is present in the blood and urine of dosed rats (Butler and Clifford, 1965...

Journal: :IP international journal of medical microbiology and tropical diseases 2021

The PT-domain of Polyketide synthase A (PksA) is crucial product template that controls the aldol cyclization and aromatization to create polyketide precursor. precursor leads biosynthesis of aflatoxin secondary metabolites. Being carcinogenic in nature these metabolic, efforts have been made explore novel inhibitors targeting PksA. Previously, [6]-gingerol reported as a prospective inhibitor f...

2011
Kenneth C. Ehrlich Qijian Wei Robert L. Brown Deepak Bhatnagar

Seeds of aflatoxin-resistant and aflatoxin-susceptible maize lines were inoculated with conidia of aflatoxin-producing Aspergillus flavus or A. parasiticus isolates or isogenic non-producing mutants. Conidia were recovered from resistant maize seed after seven days in significantly lower amounts for aflatoxin-producing A. flavus and A. parasiticus strains than for isogenic mutants incapable of ...

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