Objective: Previously, analgesic, hypnotic, and anticonvulsant effects have been suggested for Rosa damascena (R. damascena). In the present study, possible anti-seizure and neuro-protective effects of hydro-alcoholic extract of R. damascena has been investigated after inducing seizures in rats by pentylenetetrazole (PTZ). Materials and Methods: The rats were divided to five groups: (1) Control...

Due to the increasing emergence of drug resistant Tuberculosis (TB), particularly multidrug resistant TB (MDR-TB), extensive-drug resistant TB (XDR-TB) and also the development of resistance in the micro-organisms against available drugs there is a need to develop new, potent, fast-acting antibacterial and antitubercular drugs with low toxicity. With this aim different extracts of Phaseolus vul...

The alcoholic extract of Guazuma ulmifolia was evaluated for their wound healing activity in Albino Wistar rats using chemically induced wound model. The experimental animals were chemically burned by conc HCL (80%), and then divided into four groups, control, standard (Nitrofurazone 0.2% w/w), low dose (125 mg/kg) and high dose (250mg/kg). The reepithelialization was evaluated by the reducing ...

PURPOSE The purpose of this study was to investigate the effects of the hydro-alcoholic extract of Rhus coriaria seeds on the reproductive system of nicotinamide-streptozotocin-induced type-2 diabetic mice. MATERIALS AND METHODS In this experimental study, 56 male Naval Medical Research Institute mice were randomly divided into seven groups (n=8): control; diabetic mice; diabetic mice adminis...

In the present investigation, we studied the effect of alcoholic extract of Moringa oleifera (M. oleifera) seed kernels on various experimental models of bronchial asthma. Significant (P < 0. 05) increase in preconvulsion time was observed due to pretreatment with M. oleifera when the guinea pigs were exposed to either acetylcholine (Ach) or histamine aerosol. This bronchodilating effect of M. ...

INTRODUCTION Regarding chronic nature of epilepsy and its side effects and to access the effective treatment procedures, herbal medicine has received remarkable interest. The aim of this study was to determine the anticonvulsant effects of hydro-alcoholic extract of Anethum graveolens seed on pentylenetetrazol (PTZ) -induced seizure in male mice. METHODS Fifty-six albino male mice were divide...

Among the citrus species, Citrus-limonum is native of North West region of India. The petroleum ether, alcoholic and aqueous extracts of Citrus-limonum (lemon) seeds were investigated for anti-fertility effect in female albino mice. The extracts were administered orally for 7 days after insemination (i.e. post-ovulatory test). The control group received 4% gum acacia. The animals were examined ...