This study evaluated preclinical and clinical safety of marshmallow (Althaea officinalis L.) extract as a naturopathic medicine in common carp deliberately infected with Aeromonas hydrophila. The fish were fed 0 (control), 2.50, 5.00 and 10.00 g of marshmallow extract for 60 days in a preclinical experiment and then, challenged with A. hydrophila for a 10-day experime...

BACKGROUND Preanalytical variability, including biological variability and patient preparation, is an important source of variability in laboratory testing. In this study, we assessed whether a regular light meal might bias the results of routine clinical chemistry testing. METHODS We studied 17 healthy volunteers who consumed light meals containing a standardized amount of carbohydrates, pro...

Cypermethrin and beta-cyfluthrin are two most widely used multipurpose pyrethroids. After determining their oral LD50 (416.98 mg kg-1 and 354.8 mg kg-1 body weight, respectively), we assessed their hepatotoxicity in Wistar rats following acute (0.1 LD50 for 1 day) and sub-acute (0.1 LD50 for 7, 14, 21 or 28 days) poisoning. The assessment was based on hepatic marker enzymes AST, ALT, LDH, ALP, ...

BACKGROUND Host responses to periodontal disease include the production of different enzymes that are released by stromal, epithelial or inflammatory cells. There are important enzymes associated with cell injury and cell death like: aspartate and alanine aminotransferase (AST, ALT), lactate dehydrogenase (LDH), creatine kinase (CK), alkaline and acidic phosphatase (ALP, ACP), gama glutamyl tra...

Tobacco is an important cash crop of Pakistan and tremendous amount of irrational pesticides are being used to control insect growth. The frequency of plasma pesticide residues above acceptable daily intake (ADI) and its correlation with biochemical markers for assessment of adverse health effects in the tobacco farmers at district Sawabi, Pakistan was determined. Total 109 adult males consisti...

AIMS To assess the association between liver enzymes and the risk of type 2 diabetes (T2D) in a Chinese population. METHODS A nested case-control study comprising 571 T2D cases and 571 matched controls was conducted within the Singapore Chinese Health Study. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) were quant...

Abstract The present study evaluated the protective effects of silymarin extract (SIE) on cadmium chloride toxicity in common carp, Cyprinus carpio . Four experimental groups were considered for experiment including: SIE 0 (control): non-SIE-supplemented fish, 1 : fish supplemented with 400 mg SIE/kg diet, 2 1400 3 2400 diet. Fish fed diet 60 days and then exposed to (1.5 mg/l or 25% LC50-96 h)...

the present study was conducted to investigate the clinical effects and possible side effects of yarrow extract ( achillea millefolium l.) as feed additive on biochemical blood parameters and growth performance of rainbow trout ( oncorhynchus mykiss ). fishes were treated with 0 (control), 0.1, 0.5 and 1% of yarrow extract for 30 days. plasma alanine aminotransferase (alt), aspartate aminotrans...