The Front Cover shows the one-pot procedure for introduction of aminoalkyl chain through dialkyl carbonate chemistry into different phenolic substrates. This green approach is a direct alcohol substitution that avoids use chlorine giving CO2 and ethanol as only reaction by-products. proposed has numerous potential applications N,N-dialkyl ethylamine moieties are incorporated in many pharmacopho...

An efficient and easy-to-perform method was developed for immobilization of CaLB on mesoporous aminoalkyl polymer supports by bisepoxide activation. Polyacrylate resins (100-300 µm; ~50 nm pores) with different aminoalkyl functional groups (ethylamine: EA and hexylamine: HA) were modified with bisepoxides differing in the length, rigidity and hydrophobicity of the units linking the two epoxy fu...

Modified nucleosides present in the wobble position of the tRNA anticodons regulate protein translation through tuning the reading of mRNA codons. Among 40 of such nucleosides, there are modified uridines containing either a sulfur atom at the C2 position and/or a substituent at the C5 position of the nucleobase ring. It is already evidenced that tRNAs with 2-thiouridines at the wobble position...

A novel approach for the preparation of oligonucleotides carrying amino groups at the 3'-end is described. Several CPG supports having aminoalkyl groups and 3'-amino-2',3'-dideoxynucleosides linked through base-labile carbamate linkages such as 2-(2-nitrophenyl)ethoxycarbonyl and fluorenylmethoxycarbonyl were prepared using two different strategies. These supports are compatible to the standard...

3-Aminoa lky l idene-2/ / -pyran-2,4(3 / / ) -d iones (APs) , possessing a conjugated enamino moiety which is common to cyanoacrylates and 2-aminoalkyl idenecyclohexane-l ,3-diones (ACs ) , were found as a new class of photosynthetic electron transport inhibi tors. A l though the structural requi rement of APs for photosynthetic electron transport inhib i t ion was very similar to that of cyano...