OBJECTIVE To assess the correlation between the anorectal function and bladder detrusor function in patients with complete spinal cord injury (SCI) according to the type of lesion. METHODS Medical records of twenty-eight patients with SCI were included in this study. We compared the anorectal manometric and urodynamic (UD) parameters in total subjects. We analyzed the anorectal manometric and...

INTRODUCTION We identified three patients who developed anorectal stenosis after successful treatment with anti-tumor necrosis factor alpha (anti-TNF-alpha) agents. CASE PRESENTATION Two patients, a 24-year-old Irish Caucasian man and a 64-year-old Irish Caucasian woman, developed symptoms attributable to anorectal stenosis four to six weeks after treatment. A further patient, a 25-year-old I...

Introduction Children have a variety of anorectal problems that cause considerable distress to the patients and challenges to the surgeons. The presentation of these conditions may be age specific. Abscesses, fistulas, and fissures appear more commonly in infants and young children, whereas hemorrhoidal diseases are more common in older children and teenagers. The anorectal conditions discussed...

This article presents a method to fabricate, measure and control a physical simulation of the human defecatory system to investigate individual and combined effects of anorectal angle and sphincter pressure on continence. To illustrate the capabilities and clinical relevance of the work, the influence of a passive-assistive artificial anal sphincter (FENIXTM) is evaluated. A model rectum and as...

INTRODUCTION Colonic atresia and anorectal malformation are rare congenital anomalies individually. Few reports of the conditions combined in a single patient have been published in the literature. Neither colonic atresia, anorectal malformation or a combination of the disorders has previously been reported in the Haitian population. CASE PRESENTATION A 5-day-old female presented with feculen...

Anorectal melanoma is an uncommon and aggressive cancer with an unfavorable prognosis and a predilection for early infiltration and distant spread, resulting in poor overall survival. It represents approximately 1 percent of all anorectal malignancies. Between 0.4% and 1.6% of all melanomas arise in the anorectal region, and the anal canal is the most frequent site of melanoma after the skin an...

Introduction: Constipation is one of the most common complaints of individuals, which may present with complication like hemorrhoid and fissure. Hirschsprung is a disease presenting with chronic constipation and its diagnosis may be delayed until adulthood. It is diagnosed by biopsies from anorectal transitional zone. This study aimed to evaluate the association between Hirschsprung and anorect...

BACKGROUND/AIMS To date, high-resolution manometry has been used mainly in the study of esophageal motility disorders and has been shown to provide more physiological information than conventional manometry, and is easier to interpret. This study aimed to evaluate the usefulness of high-resolution anorectal manometry (HRARM) compared to water-perfused anorectal manometry. METHODS Patients who...

BACKGROUND Anorectal transplantation is a method for patients who have lost their anorectal function or suffer from congenital anorectal dysfunction to recover this function, and this has been investigated in experimental animal models using pigs, dogs, and rats. In this study, we performed an examination of anorectal transplantation in human cadavers to investigate whether this procedure could...

BACKGROUND Anismus is thought to be a cause of chronic constipation by producing outlet obstruction. The underlying mechanism is paradoxical contraction of the anal sphincter or puborectalis muscle. However, paradoxical sphincter contraction (PSC) also occurs in healthy controls, so anismus may be diagnosed too often because it may be based on a non-specific finding related to untoward conditio...