نتایج جستجو برای: antagonist
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Background: Temporal lobe epilepsy is a chronic neurological disorder characterized by spontaneous seizures, learning and memory deficiency, loss of neurons, mossy fiber sprouting and tissue apoptosis. This study was to investigate the effect of NOP receptor agonist (MCOPPB) and antagonist (SB612111) on seizure and cognitive dysfunction and histological studies in experimental model of temporal...
Background: Polycystic ovarian syndrome (PCOS) is the most common endocrinological disorders that affect approximately 5-7% of women in reproductive age. There is not any consensus about the efficient in vitro fertilization (IVF) protocol for patients with PCOS. The aim of the present study was to compare the half and one-third dose depot gonadotropin-releasing hormone (GnRH) agonist protocols ...
Background: During in vitro fertilization (IVF), fertility patients are expected to self-administer many injections as part of this treatment. While newer medications have been developed to substantially reduce the number of these injections, such agents are typically much more expensive. Considering these differences in both cost and number of injections, this study compared patient preference...
The number of 88 rats was chosen, after 21 days, they were ablactated and categorized them as following groups:
 control group 1 has a cage 8 in social condition. After 6 weeks saline injection (1mg / kg), the yawning behavior is recorded for 60 minutes. Group 2 conditions receiving ethanol months, each serving 600 mg kg. 3 isolation without treatment with agonist antagonist, Opioid alcoho...
Chemotherapy induced nausea and vomiting (CINV) are the most common side effects that impacts quality of life in children receiving cancer treatment. Inadequately controlled CINV impairs functional activity increases healthcare utilization compromises treatment adherence. The availability new antiemetic agents results substantially improvement emetic control; however, real-world practice, many ...
the aim of this study was to evaluate the outcomes of adding low-dose hcg (human chorionic gonadotropin), as an lh active supplement, to a gnrh antagonist protocol in patients undergoing assisted reproduction techniques. in this parallel-group randomized clinical trial, 137 infertile female outpatients aged 20 - 39 years were randomized into two groups: hcg group and non-hcg group. all patients...
background: the pathogenesis of inflammatory bowel disease is complex and multifactorial. studies have led to the current concept that toll-like receptors represent key mediators of innate host defense in the intestine, and they are involved in maintaining mucosal as well as commensal homeostasis. we studied the possibility of simvastatin and antagonist of receptors of interleukin-1 for pharmac...
rosemary (rosmarinus officinalis) is a common household plant grows in many parts of the world, including iran. rosemary leaves are used in folk medicine as an antispasmodic, analgesic, diuretic and ntiepileptic agent. the objective of this study was to investigate the antinociceptive mechanisms of rosemary extract using a writhing test as a model of visceral pain. possible antinociceptive mech...
the effects of cholecystokinin (cck) receptor antagonists on hypothermia induced by cocaine or morphine have been studied in mice. in the present work, subcutaneous (sc) injection of cocaine (50-150 mg/kg) or morphine (125-500 mg/kg) induced hypothermia in mice. administration of ccka receptor antagonist mk-329 (0.5-1.5 mg/kg), cckb receptor antagonist l-365, 260 (0.5-1.5 mgl kg) and cck recept...
Background: Male factors, mainly spermatogenesis disorder, are responsible for 20-30% of infertility occurs in different societies. One of the known causes of spermatogenesis disorder is chemotherapy in patients with cancer. The side effect of chemotherapic agents may last from 10 years up to the end of the life. Since dividing cells are mainly affected by anticancer drugs, the aim of the prese...
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