Solution behaviour prevailing in L-Asparagine two aqueous ionic liquid solutions, namely (Benzyl tri–methyl ammonium chloride; Benzyl tri-ethyl chloride) have been studied by investigation of physico-chemical parameters; density, viscosity, refractive index, conductance and surface tension measurement respectively. The nature interactions occurring the solution calculated on basis apparent mola...

Molecular dynamics simulations of myoglobin and aspartate aminotransferase, with explicit solvent, are shown to accurately reproduce the experimentally measured molar volumes. Single aminoacid substitution at VAL39 of aspartate aminotransferase is known to produce large volumetric changes in the enzyme, and this effect is demonstrated in simulation as well. This molecular dynamics approach, whi...

The densities of thirteen silicate liquids along the NaZSiOs-TiOz and CaSiOs-TiOZ joins and six other titanium-bung silicate liquids of the general formula X ;$,TiSiO, (where X = Li, Na, K, Rb, Cs, Ca, Sr, Ba) have been measured in equilibrium with air using the double Pt bob Archimedean method. The NazSiOj-TiOz join was investigated from lo-50 mole% Ti02 in the temperature range lOOOI 150°C wh...

The equilibrium dissociation of recombinant human IFN-gamma was monitored as a function of pressure and sucrose concentration. The partial molar volume change for dissociation was -209 +/- 13 ml/mol of dimer. The specific molar surface area change for dissociation was 12.7 +/- 1.6 nm2/molecule of dimer. The first-order aggregation rate of recombinant human IFN-gamma in 0.45 M guanidine hydrochl...

In this article the behavior of tetrahydrofuran (THF) + 2-alkanol namely 2-propanol, 2-butanol, 2-pentanol, 2-hexanol and 2-heptanol binary mixtures through the density and viscosity measurements have been studied as a function of composition and within the temperature range of 293.15–313.15 K. The excess molar volume, isobaric thermal expansivity, partial molar volumes, and viscosity deviation...

The aim of this study was to prepare liposomes of acyclovir (ACY) by thin layer evaporation (TLE) and reverse phase evaporation (REV) methods. Twenty-seven batches of liposomes from each method were prepared using technique of three variables at three levels (33) factorial design. Drug/Lipid (molar ratio), hydration volume and hydration time were considered three independent variables in TLE me...

Methionine is an amino acid that extremely important for human health. To better understand the biochemical events occurring in body, excess molar properties of methionine and aqueous ethanol methanol mixtures were determined at 298.15 K. Interactions between components solutions are explained. Negative deviations from ideal state have been observed due to hydrogen bonds, dipole interactions, c...

The present paper reports the study of binary mixtures and their properties over the entire range of composition at temperatures 288, 298, 308 and 318 K. Excess dielectric constant, excess molar volume, excess refractive index, molar refraction and excess molar refraction at different temperatures have been computed from the experimentally measured values of the aforesaid parameters and fitted ...