In humans, coronary blood flow is tightly regulated by microvessels within the myocardium to match myocardial energy demand. However, evidence regarding inherent sensitivity of the microvessels to changes in arterial partial pressure of carbon dioxide and oxygen is conflicting because of the accompanied changes in myocardial energy requirements. This study aimed to investigate the changes in co...

Background and Objectives: Suction is a necessary and common method which aids in the release of secretion from the respiratory system for the patients who have undergone mechanical ventilation. One of the most common complications of suction is hypoxemia which causes dysrhythmia and death. The purpose of this study was to determine the effects of open and closed-endotracheal suction on cardiov...

results fifty-seven patients were enrolled; 35 patients (62.5 %) were male. the mean of etco2 and paco2 of patients were 41.49 ± 9.80 and 64.74 ± 9.76, respectively. the mean of paco2 was significantly more than the means of etco2 in patients with copd. the association between arterial bicarbonate and etco2 was weak and not significant (p = 0.136 and r = 0.04). conclusions capnography can be us...

High dose buprenorphine is used as substitution treatment in human heroin addiction. Deaths have been reported in addicts using buprenorphine, frequently in association with benzodiazepines. In the current study, we observed the effects of buprenorphine and midazolam alone and in combination on arterial blood gases. Four groups of 10 male Sprague-Dawley rats received a parenteral injection of a...

INTRODUCTION In chronic alveolar hypoventilation, previous studies of selected patient groups have shown that nocturnal home mechanical ventilation (HMV) may result in improvements in chronic blood gas disturbances during daytime spontaneous breathing. We wished to examine the effects of this treatment in a large sample of non-selected patients prospectively followed up, in a national multicent...

We evaluated whether arterial blood samples for pH and blood gas analysis need to be transported on ice. We found that although the changes in pH, pCO2 and pO2 were greater in samples kept at room temperature versus those kept on ice, the difference was probably not of clinical significance until the period of time after arterial puncture exceeded 20 minutes. We recommend that arterial blood sa...