Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and phosphatidylserine (PS) externalization in a cohort of adult ITP patients. Apoptosis was not related to platelet activation, as PAC-1 binding, P-selectin ex...

This study aimed to assess the ability of an auto-nasal continuous positive airway pressure (nCPAP) device (REM + auto; NPBFD, Nancy, France) to predict the optimal constant nCPAP level. The apnoea/hypopnoea detection facility of the auto-nCPAP device was deliberately disabled and nasal mask pressure vibration detection was the only mode of pressure setting. The auto-nCPAP device was tested on ...

Non-Gaussianity index (λ) is a new index of heart rate variability (HRV) that characterizes increased probability of the large heart rate deviations from its trend. A previous study has reported that increased λ is an independent mortality predictor among patients with chronic heart failure. The present study examined predictive value of λ in patients after acute myocardial infarction (AMI). Am...

Clustering is a useful technique that divides data points into groups, also known as clusters, such that the data points of the same cluster exhibit similar properties. Typical clustering algorithms assign each data point to at least one cluster. However, in practical datasets like microarray gene dataset, only a subset of the genes are highly correlated and the dataset is often polluted with a...

The Gini index does not give a strictly consistent scoring function. Therefore, simply maximizing the may lead to wrong model choice. main issue is that rank-based score calibration-sensitive. We show allows for if we restrict it class of auto-calibrated regression models. That is, on models know true maximizes index.

The main purpose of ...

one of the possible ways to ensure future food needs of an increasing world population involves the better water use through the development of crop varieties which need less water and are more tolerant to drought. in order to study the response of twenty landraces of bread wheat to drought stress, an experiment was conducted in a randomized complete block design with three replications under t...

AIMS To assess the proliferative activity of gestational trophoblastic disease (GTD) using one of the novel proliferation markers (MCM7) and to determine its prognostic value in hydatidiform mole (HM). METHODS AND RESULTS Immunohistochemical staining for MCM7 was performed on 122 samples of paraffin-embedded trophoblastic tissues including 22 normal first-trimester placentas, 12 term placenta...

‎for a finite group $g$ let $nu(g)$ denote the number of conjugacy classes of non-normal subgroups of $g$‎. ‎the aim of this paper is to classify all the non-nilpotent groups with $nu(g)=3$‎.