One of the most successful applications of atomic force microscopy (AFM) in biology involves monitoring the effect of force on single biological molecules, often referred to as force spectroscopy. Such studies generally entail the application of pulling forces of different magnitudes and velocities upon individual molecules to resolve individualistic unfolding/separation pathways and the quanti...

The application of magnesium alloys is greatly limited because of their relatively low strength and ductility. An effective way to improve the mechanical properties of magnesium alloy is to refine the grains. As the race for better materials performance is never ending, attempts to develop viable techniques for microstructure refinement continue. Further refining of grain size requires, however...

Motivated by recent experiments showing the compressive buckling of microtubules in cells, we study theoretically the mechanical response of and force propagation along elastic filaments embedded in a non-linear elastic medium. We find that embedded microtubules buckle when their compressive load exceeds a critical value fc, and that the resulting deformation is restricted to a penetration dept...

This paper proposes, for low buildings, an integrated wall structure of a brick-stem-insulating layer, which plays a major part in both heat preservation and force bearing. The research team has tested the thermal performance of the structure, the results of which are satisfying. To further study the force-bearing performance, the paper carries out compressive tests of specimens of different st...

geometric and material nonlinear behavior of slender webs in i-column girders having stocky flanges under the action of combined lateral and axial loads is investigated. interaction curves corresponding to the application of compressive and shear loads at buckling and ultimate stages for both web plates and column sections are plotted. in addition, the effects of flange and web slenderness rati...

The mechanical state encoded by group III and IV muscle afferents, putative mechano-nociceptors, during indentation was examined using an isolated muscle-nerve preparation in a rat model. Gracilis muscle and its intact innervation were surgically removed from the medial thigh of the rat hindlimb and placed in a dish containing rodent synthetic interstitial fluid. The tendons of the muscle were ...

The mechanical state encoded by slowly adapting type 1 mechanoreceptors (SAI) during indentation was examined using an isolated preparation in a rat model. Skin and its intact innervation were harvested from the medial thigh of the rat hindlimb and placed in a dish, with the corium side down, containing synthetic interstitial fluid. The margins of the skin were coupled to an apparatus that coul...

The incremental sheet metal forming (ISMF) process is a new and flexible method that is well suited for small batch production or prototyping. This paper studies the use of the finite element method in the incremental forming process of AA1050 sheets to investigate the influence of tool diameter, vertical step size, and friction coefficient on forming force, spring-back, and thickness distribut...

Using the formula of shear bearing force of oblique cross section in eccentrically loaded column, we analyze the stress acting on short-leg shear wall and conventional eccentrically loaded column. We propose the formula for calculating the shear bearing force of oblique cross section of short-leg shear wall that considers the action of vertical reinforcing steel bars, flange and axial compressi...