The infection of Streptococcus pyogenes T25(3) with the temperate bacteriophage T12 results in the conversion of the nontoxigenic strain to type A streptococcal exotoxin (erythrogenic toxin) production. Although previous research has established that integration of the bacteriophage genome into the host chromosome is not essential for exotoxin production, the location of the gene on the bacteri...

Objective(s): Bacteriophages are infectious replicating entities that are under consideration as antimicrobial bioagents to control bacterial infections. As an alternative or supplement to antibiotics, bacteriophages can be used to circumvent the resistance to existing antibiotics. The aim of this study was to assess the synergistic effect of a naturally isolated phage...

The protein product of gene 11 of bacteriophage T4D was purified to apparent homogeneity from a bacteriophage culture in which this particular structural protein had not yet become incorporated into the mature bacteriophage particle. Monomer and apparent trimer molecular weights were determined to be approximately 24,000 and 70,000, respectively, and an amino acid analysis was performed. The ki...

1. Bacteriophage active against four species of bacteria was found in a salt solution extract of house flies. 2. A growth-inhibiting principle, not bacteriophage, active against four other species of bacteria was found to be present in the same extract. 3. An attempt to secure streptococcus bacteriophage by feeding to flies a streptococcus susceptible to the inhibitor but not to the bacteriopha...

This study investigated the antiviral effect of silver nanoparticles on MS2 bacteriophage. Silver nanoparticles were synthesized via chemical reduction method and characterized by transmission electron microscope. Synthesized silver nanoparticles and cultivated MS2 bacteriophage were characterized using zetasizer. The result in this study indicates that the toxicity of silver nanoparticles on M...

Campylobacter jejuni is a leading cause of food-borne illness. Although a natural reservoir of the pathogen is domestic poultry, the degree of genomic diversity exhibited by the species limits the application of epidemiological methods to trace specific infection sources. Bacteriophage predation is a common burden placed upon C. jejuni populations in the avian gut, and we show that amongst C. j...

Restriction-modification systems are widespread genetic elements that protect bacteria from bacteriophage infections by recognizing and cleaving heterologous DNA at short, well-defined sequences called restriction sites. Bioinformatic evidence shows that restriction sites are significantly underrepresented in bacteriophage genomes, presumably because bacteriophages with fewer restriction sites ...

Lysates of the virulent bacteriophage SPP1 were shown to be capable of mediating generalized transduction. Suppressible mutants of this bacteriophage (sus) were capable of transduction at a lower multiplicity of infection than virulent SPP1. Linkage analysis demonstrated that bacteriophage SPP1 transduced segments of the genome equal in size to that transferred by SP10. This bacteriophage shoul...

course of bacteriophage without medical a vie . Although it is impossible to obtain any ie la e information as regards the actual amoun o bacteriophage used in a city such as Calcutta, from certain information that we have been a e gather, it appears that approximate y a million ampoules of bacteriophage are consume annually in Calcutta. The number of firms wno market preparations of bacterioph...