In this paper, we study an integrated production scheduling and delivery routing problem. The manufacturer has to schedule a set of jobs on a single machine without preemption and to deliver them to multiple customers. A single vehicle with limited capacity is used for the delivery. For each job are associated: a processing time, a size and a specific customer location. The problem consists the...

A packet-switching algorithm specifies the actions of the nodes in order to deliver packets in the network. A packet-switching algorithm is universal if it applies to any network topology and for any batch communication problem on the network. A long standing open problem has concerned the existence of a universal packet-switching algorithm with near optimal performance guarantees for the class...

Delivery drones typically perform delivery by suspending the parcel vertically or landing drone to drop off package. However, because of constrained area and requirement for precise navigation, delivering items customers who reside in multi-story apartment complexes poses a unique challenge. This research paper proposes novel system buildings with balconies that employ two methods Vertical Grid...

This contribution presents algorithms, methods, and software for a Grid resource manager, responsible for resource brokering and scheduling in early production Grids. The broker selects computing resources based on actual job requirements and a number of criteria identifying the available resources, with the aim to minimize the total time to delivery for the individual application. The total ti...

BACKGROUND Single-use rocking-motion-type bag bioreactors provide advantages compared to standard stirred tank bioreactors by decreased contamination risks, reduction of cleaning and sterilization time, lower investment costs, and simple and cheaper validation. Currently, they are widely used for cell cultures although their use for small and medium scale production of recombinant proteins with...

In this paper, we study an integrated production an outbound delivery scheduling problem with a predefined sequence. The manufacturer has to process a set of jobs on a single machine and deliver them in batches to multiple customers. A single vehicle with limited capacity is used for the delivery. Each job has a processing time and a specific customer location. Starting from the manufacturer lo...

This document defines a MIME content type suitable for tunneling an ESMTP [RFC-821, RFC-1869] transaction through any MIME-capable transport. This type can be used for a variety of purposes, including: Extending end-to-end MIME-based security services (e.g., [RFC-1847]) to cover message envelope information as well as message content. Making it possible to use specific SMTP extensions such as N...

 It is scientifically challenging to determine the inventory level all through the supply chain in such a way that the desired objectives such as effectiveness and responsiveness of the supply chain system can be obtained. Simulation is a means for solving various problems which cannot be solved by regular exact models such as mathematical ones due to their complexity. The present paper is aime...

The Parenteral administration route is the most effective and common form of delivery for active drug substances with poor bio-availability and the drugs with a narrow therapeutic index. Though parenteral administration of drug is often critical and associated with problems such as limited number of acceptable excipients, stringent requirements of aseptic production process, safety issues, pati...