The size of repair patch made by E. coli DNA polymerase I (Poll) following the removal of a thymine-psoralen monoadduct by E. coli (A)BC excinuclease was determined by using an M13mp19 DNA with a single psoralen monoadduct at the polylinker region. Incubation of this substrate with (A)BC excinuclease, Poll and a combination of 3 dnTP plus 1 dNTP(alpha S) for each nucleotide, and DNA ligase resu...

[1] This study examines the short‐term (∼15 year) effects of controlling fossil‐fuel soot (FS) (black carbon (BC), primary organic matter (POM), and S(IV) (H2SO4(aq), HSO4 , and SO4 )), solid‐biofuel soot and gases (BSG) (BC, POM, S(IV), K, Na, Ca, Mg, NH4 , NO3 , Cl and several dozen gases, including CO2 and CH4), and methane on global and Arctic temperatures, cloudiness, precipitation, and at...

HER2(+) breast cancer (BC) is a highly aggressive subtype, affecting ~20% of BC patients. Current treatments include adjuvant or neoadjuvant chemotherapy plus anti-HER2 agents such as trastuzumab, a monoclonal antibody directed against HER2. Despite improvement in disease free survival, most patients eventually succumb to metastatic disease, which is largely incurable. Consequently, there is an...

OBJECTIVES To study mother to child HIV-1 transmission (MTCT) and infant mortality following benzalkonium chloride (BC) disinfection. METHODS A randomised, double blind phase II placebo controlled trial. Women testing positive for HIV-1 infection in prenatal care units in Abidjan, Côte d'Ivoire, and Bobo-Dioulasso, Burkina Faso, from November 1996 to April 1997 were eligible, with their infor...

The present work introduces and justiies the notion of hy-perrobust learning where one xed learner has to learn all functions in a given class plus their images under primitive recursive operators. The following is shown: This notion of learnability does not change if the class of primitive recursive operators is replaced by a larger enumerable class of operators. A class is hyperrobustly Ex-le...

Legumain (LGMN) is highly expressed in breast cancer (BC) and other solid tumors and is a potential anticancer target. Here we investigate the anti-tumor effects of short hairpin RNAs (shRNAs) targeting LGMN embedded in a microRNA-155 (miR-155) architecture, which is driven by a radiation-inducible chimeric RNA polymerase II (Pol II) promoter. Lentiviral vectors were generated with the chimeric...

Bacterial cellulose (BC) synthesized by Gluconacetobacter sucrofermentans has a high degree of crystallinity, durability, great resistance, and biocompatibility. This study evaluates the effect that carbon and nitrogen sources, present in HS (Hestrin–Schramm) culture medium, have on BC from G. sucrofermentans CECT 7291 used to restore damaged documents. The initial pH of the medium and the temp...

Static defluoridation of high fluoride (10-12 ppm) water by sixteen different combinations of tricalcium phosphate (TCP), bone char (BC), hydroxyapatite (HAP), and related substances has been investigated. Defluoridation of 100 mL of the water by 300 mg of relatively insoluble phosphates is only 60-70 percent complete. Defluoridation is 30 percent more efficient, however, when a more soluble ph...

The capacity region of the Gaussian multiple-input, single-output (per user) Broadcast Channel (BC) using superposition coding is analyzed. Perfect channel state information is assumed both at the transmitter and the receivers. The achievable Signal-to-Interference-plus-Noise Ratio (SINR) region of BC and MAC using beamforming is considered, and it is shown that existing SINR-balancing results ...