We report reactions of LiNacNac and NacNacMg(TMP) with common organic substrates (TMP = 2,2,6,6-tetramethylpiperidide). Using bulky β-diketiminate compound, NacNac (Me, Dipp) we have trapped metallated intermediates amenable to X-ray crystallographic study. acetone produced the NacNac-free hexameric diacetone alkoxide [{LiO(MeC(=O)CH2C(Me)2}6]; whereas pinacolone gave simple monomeric donor-acc...

We evaluated the bactericidal activities of 35 benzaldehydes, 34 benzoic acids, and 1 benzoic acid methyl ester against Campylobacter jejuni, Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella enterica when these compounds were substituted on the benzene ring with 0, 1, 2, or 3 hydroxy (OH) and/or methoxy (OCH3) groups in a pH 7.0 buffer. Dose-response plots were used to determine...

3, 5-Cyclohexadiene1, 2-diol1-carboxylic acid (1, 2-dihydro1, 2-dihydroxybenzoic acid) is converted enzymatically to catechol in cell extracts from Acinetobacter, Alcaligenes, Azotobacter, and three Pseudomonas species. This enzymatic activity is present only in cultures which have been grown in the presence of benzoic acid, and which convert benzoic acid to catechol rather than to protocatechu...

The problem of the origin of the glycine available for hippuric acid synthesis after the administration of benzoic acid or its salts has been studied by many investigators with varying results. It should be borne in mind, in this connection, that all species of animals do not react similarly in response to the ingestion of benzoic acid. Thus the organisms of man (l), the rabbit (2), the goat (3...

The mechanisms by which the weak acid preservative benzoic acid inhibits the growth of Saccharomyces cerevisiae have been investigated. A reduction in the pyruvate kinase level, which decreases glycolytic flux, did not increase the sensitivity of yeast to benzoic acid. However, a decrease in 6-phosphofructo-1-kinase (PF1K), which does not affect glycolytic flux, did increase sensitivity to benz...

The benzoic and cinnamic acids found in forages were tested for their inhibitory effects on digestion of cellulose and hemicellulose by mixed cultures of rumen microorganisms in vitro. Rate and extent of cellulose digestion with the addition of cinnamic acids were determined. The benzoic acids and aldehydes were also compared for their inhibitory potential. Of the benzoic acid derivatives, only...

The aim of this study is to estimate dietary intake of benzoic acid and its salts through food additives in adult population of South East Serbia. Information on dietary intake among 620 adults (aged 18-65) was collected using a food frequency questionnaire, and 748 food samples were analyzed. The mean estimated intake of benzoic acid -0.32 mg/kg of body weight (bw) per day was below acceptable...

The title compound [systematic name: benzoic acid-pyrrolidin-1-ium-2-carboxyl-ate (1/1)], C7H6O2·C5H9NO2, is an example of the application of non-centrosymmetric co-crystallization for the growth of a crystal containing a typically centrosymmetric component in a chiral space group. It co-crystallizes in the space group P212121 and contains benzoic acid and l-proline in equal proportions. The cr...

The roles of benzoic acid and water on the Michael reaction of pentanal and nitrostyrene catalyzed by diarylprolinol silyl ether are revealed by density functional theory calculations. The calculations demonstrate that the benzoic acid is ready to attack the catalysts and form a hydrogen bond between the hydrogen atom of the COOH of benzoic acid and one of the N atoms of the catalyst. The compl...

Benzoic acid is oxidized by certain Mycobacteria (1). They do not oxidize it completely to carbon dioxide and water; the oxygen uptake usually stops when 5 atoms of oxygen are utilized for each molecule of benzoic acid. The enzymes concerned are adaptive, and are rapidly formed when small amounts of benzoic acid are added to suspensions of the bacteria (2). Benzoic acid may be considered somewh...