B ONE MARROW LYMPHOCYTOSIS (BML) occurring during remission of acute leukemia is commonly believed to be a poor prognostic sign that max’ presage early subsequent relapse. In 1956, the Clinical Studies Panel of the Cancer Chemotherapy National Service Center published its criteria for the evaluation of response to treatment in acute leukemia.1 They recommended that patients having significant B...

OBJECTIVE To predict, using clinical and qMRI data, the incidence of total knee replacement (TKR) during the long-term follow-up of knee osteoarthritis (OA) patients who formerly received chondroitin sulfate (CS) or placebo treatment. DESIGN A post hoc intention-to-treat analysis to evaluate the incidence of TKR was done on knee OA patients who had participated in a 12-month trial evaluating ...

Objective: Evaluate the evidence of clinical correlation between vitamin D and symptomatic degenerative joint disease. Methods: A systematic search meta-analysis was conducted randomized controlled studies (RCTs) published in January 1st, 2010, March 30th, 2020 on five different databases. The study population consisted adult patients with knee osteoarthritis; intervention D; comparison placebo...

BACKGROUND Whether the increase in vascular disease prevalence and mortality in OA populations is a result of co-occurrence of cardiovascular disease and OA, which are both common in the older population, is due to OA treatments or to the common association with reduced physical activity and/or obesity is unclear. One way to explore this non-invasively is to examine the cross-sectional relation...

isolated extramedullary relapse of chronic myelogenous leukemia (cml) after allogeneic stem cell transplant is rare. there is a case report of a child who developed a granulocytic sarcoma of the maxillary and sphenoid sinuses and lumbosacral spinal cord mass 18 months after allogeneic bone marrow transplant for cml. he was presented with per orbital edema and neurological deficit of lower extre...

BACKGROUND Benign metastasizing leiomyoma (BML) occurs in a low proportion of uterine leiomyomas and treatment methods for BML are diverse and controversial. The study introduces preliminary experiences in the diagnosis and treatment of BML with the purpose of finding a suitable management strategy for these patients. METHODS Three patients with BML were treated in our department from April 2...

BACKGROUND Subchondral bone marrow lesions (BMLs) play a key role in the pathogenesis of osteoarthritis (OA) and are associated with pain and structural progression in knee OA. However, little is known about clinical significance and determinants of BMLs of the knee joint in younger adults. We aimed to describe the prevalence and environmental (physical activity), structural (cartilage defects,...

BACKGROUND Choice of appropriate MR pulse sequence is important for any research studies using imaging-derived data. The aim of this study was to compare semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts using intermediate-weighted (IW) fat-suppressed (fs) spin echo and Dual Echo Steady State (DESS) sequences on 3 T MRI. METHODS Included were 201 ...