In the rare hereditary bone disorder of osteopetrosis, reduced bone resorption function leads to both the development of densely sclerotic fragile bones and progressive obliteration of the marrow spaces and cranial foramina. Marrow obliteration, typically associated with extramedullary hemopoiesis and hepatosplenomegaly, results in anemia and thrombocytopenia and nerve entrapment accounts for p...

Introduction: Various bone palliative therapeutic agents have been developed and widely used for bone metastasis such as 153Sm-EDTMP. In this study, production, quality control and biodistribution studies of a newly developed therapeutic compound have been presented followed by imaging studies in wild-type rodents. Methods: 153Sm-TTHMP was prepared starting from 153<...

BACKGROUND AND AIM: Nasal fracture is one of the most common facial fractures and the main goal of this study was evaluation of closed reduction surgery of nasal bone fractures.METHODS: Thirty six patients including 24 male and 12 female patients suffered from nasal bone fractures were treated by closed reduction method. Preoperative and postoperative computed tomographic scans were analyzed by...

Background: Type 2 diabetes (T2D) in the elderly is an epidemic that has major impact on global health. Thus this experimental study aimed to compare the response of microRNA-133a (miR-133a) in different tissues and of Runt-related transcription factor 2 (Runx2) in bone marrow tissue following resistance and endurance training in old rats with high-fat diet and streptozotocin (HFD/STZ)-induced ...

objective: vertical bone loss evaluations in the nobel biocare replace® select tapered tm implant system in the human after one-year loading time. materials and methods: this retrospective cross-sectional study was performed on 31 patients (14 men, 17 women; mean age, 60.39 years) receiving 170 implants (mean, 5.48 for each patient) of groovy and non-groovy designs in the nobel biocare replace®...

introduction: nowadays various bone pain palliative therapeutic agents have been developed for bone metastases. among those, 153sm-ethylenediamine tetramethylene phosphonic acid (153sm-edtmp) is the major therapeutic agent which is widely used in the world. in this study, production, quality control and biodistribution studies of this therapeutic radiopharmaceutical have been presented and foll...

abstract        background and objective: osteoporosis is one of the complications of diabetes. the aim of this study was to determine the impact of resistance training along with portulaca oleracea supplementation on opg and nfκb levels (bone markers) in women with type ii diabetes.        methods: overall, 28 women with type ii diabetes (44 to 60 years old) were randomly and equally assigned ...

in the rare hereditary bone disorder of osteopetrosis, reduced bone resorption function leads to both the development of densely sclerotic fragile bones and progressive obliteration of the marrow spaces and cranial foramina. marrow obliteration, typically associated with extramedullary hemopoiesis and hepatosplenomegaly, results in anemia and thrombocytopenia and nerve entrapment accounts for p...