Long-term kidney graft survival is affected by different variables including donor condition, ischemia-reperfusion injury, and graft rejection during the transplantation process. The complement system is an important mediator of renal ischemia-reperfusion injury and in rejecting allografts. However, donor complement C3 seems to be crucial in renal transplantation-related injury as renal injury ...

The main factor limiting organ donation is the availability of suitable donors and organs. Currently, most transplants follow multiple organ retrieval from heartbeating brain-dead organ donors. However, brain death is often associated with marked physiological instability, which, if not managed, can lead to deterioration in organ function before retrieval. In some cases, this prevents successfu...

conclusions our comprehensive literature review showed that our study was the first investigation in iran and the region, which determined the prevalence of nafld based on tissue diagnosis. we believe that the prevalence of nafld/nash in our donors can represent the overall prevalence in this age group in iran. results among 116 cases, two were diagnosed as probable nash. there was a significan...

Liver transplantation, is the replacement of unhealthy liver with a new liver allograft. This surgical procedure is now widely common all over the world in various medical centers. The major limiting factors of this surgery is the lack of available donors and decreased chance of appropriate patient selection. Anesthetic management of organ donors includes intensive management of heart beating a...

Demand for organ donation is increasing over the years in all age groups leading search for alternative sources. Donation pool expansion in newborns necessitates new approaches specifically for brain and circulatory death definition. The “dead donor rule” (the donor must be dead before organ removal starts) remains the cornerstone for organ procurement. Brain death definition and time determina...