OBJECTIVE To evaluate food intake, occurrence of energy-protein malnutrition and anemia, and intestinal iron absorption in children with chronic liver disease. METHODS The study included 25 children with chronic liver disease, 14 with cholestasis and 11 without cholestasis. The age varied between 6.5 months and 12.1 years. Intestinal iron absorption was evaluated by the increment of serum iro...

cholestatic hepatitis induced by prolonged administration of nalidixic acid: anti biotics like other drugs may generally produce hepatic benign lesions. we have recently observed a case of cholestatic hepatitis by prolonged administration of nalidixic acid. this hepatitis have regressed rapidly after discont inuin-c the dru g. this case dose not excluded the value of nalidixic acid asa strong a...

Cholestatic hepatitis is identified as one of the features of hypopituitarism in the newborn, but the exact etiology of cholestasis in these cases has not been well established yet. We report here two infants, one with isolated glucocorticoid deficiency and the other with multiple pituitary hormone deficiency, indicating primary and central adrenal insufficiency, respectively, who presented wit...

Cholestatic drug-induced liver injury (DILI) can be a diagnostic challenge due to a large differential diagnosis, variability in clinical presentation, and lack of serologic biomarkers associated with this condition. The clinical presentation of drug-induced cholestasis includes bland cholestasis, cholestatic hepatitis, secondary sclerosing cholangitis, and vanishing bile duct syndrome. The ass...

Background: Altered hepatobiliary status has been reported in association with COVID-19 which linked, limited evidence, to the exaggerated COVID-19-induced hyper-inflammatory response. Hence, current study evaluated hepatocellular and its indicators of inflammation among patients. Methods: This was conducted RT-PCR-confirmed treatment-naïve patients Port Harcourt, South-south Nigeria. Pre-medic...

BACKGROUND AND OBJECTIVE Cholestatic jaundice in early infancy is a difficult diagnostic problem. Early diagnosis is important for proper management. This retrospective study was conducted to find out the etiology and clinical profile of neonatal cholestatic disorders in Bangladesh. SETTING Tertiary-care hospital in a developing country. METHODS Clinical profile and cause of cholestatic ill...