Background: Chronic idiopathic urticaria is defined as urticaria, which lasts for more than 8 weeks and has no apparent etiology. The aim of this study was to examine the causal role of Helicobacter pylori infection in chronic idiopathic urticaria. Methods: Fifty-six patients with chronic idiopathic urticaria and a negative response to skin prick test for common aeroallergens were selected. The...

introduction: immune system is involved in the etiology and pathophysiology of inflammation and vitamins are important sources of substances inducing nonspecific immunomodulatory effects. given the proinflammatory role of cytokines in the inflammation and pain induction, this study aimed to assess the effects of long-term administration of vitamin b1 on the proinflammatory cytokines, edema, and...

s100ß a neurotrophic factor mainly released by astrocytes, has been implicated in the pathogenesis of bipolar disorder. thus, lithium may exert its neuroprotective effects to some extent through s100ß. furthermore, the possible effects of lithium on astrocytes as well as on interactions between neurons and astrocytes as a part of its mechanisms of actions are unknown. this study was undertaken...

background: treatment of chronic constipation is creating one of the major problems for doctors and patients. pyridostigmine increases the gastrointestinal motility through the effects on cholinesterase. it seems that this mechanism can reduce chronic constipation. the aim of this study was to compare the effects of pyridostigmine and bisacodyl on chronic constipation. methods: this study was c...

We present the frailtyHL package for fitting semi-parametric frailty models using hlikelihood. This package allows lognormal or gamma frailties for random-effect distribution, and it fits shared or multilevel frailty models for correlated survival data. Functions are provided to format and summarize the frailtyHL results. The estimates of fixed effects and frailty parameters and their standard ...

background and objective: recent studies have shown that anticholinergic alkaloids compounds have strong analgesic effects. due to presence of anticholinergic alkaloids in hyoscyamus niger and its mentioned effects in iranian traditional medicine, its analgesic effects were assessed. at first, acute and chronic pain thresholds in male nmri rats with formalin test was evaluated, then oral and in...

background oxidative stress plays a major pathogenic role in liver injury following chronic hepatitis b. glutathione peroxidase (gpx) has a central role in regulating the oxidative state. hepatitis b virus (hbv) results in down-regulation of gpx. on the other hand, iron homeostasis is disrupted in hbv infected patients. therefore, the objective of this study was to assess the interplay of gpx a...

Now, we come to offer you the right catalogues of book to open. optimal design of blocked and split plot experiments is one of the literary work in this world in suitable to be reading material. That's not only this book gives reference, but also it will show you the amazing benefits of reading a book. Developing your countless minds is needed; moreover you are kind of people with great curiosi...

The Choice Between Fixed and Random Effects Models: Some Considerations for Educational Research We discuss fixed and random effects models in the context of educational research and set out the assumptions behind the two approaches. To illustrate the issues, we analyse the determinants of pupil achievement in primary school, using data from the Avon Longitudinal Study of Parents and Children. ...