نتایج جستجو برای: conjugate hl
تعداد نتایج: 52212 فیلتر نتایج به سال:
Introduction: Children learn to communicate by hearing sounds. If there is hearing loss, the cognitive and speaking abilities and language learning will deteriorate. Early detection and intervention are important factors in the successful treatment of hearing loss in children. Hearing loss (HL) is divided into two main groups: conductive hearing loss (CHL) and sensorineural hearing loss (SNHL)...
BACKGROUND Brentuximab vedotin is a CD30-directed antibody-drug conjugate. Retreatment with brentuximab vedotin monotherapy was investigated in patients with CD30-positive Hodgkin lymphoma (HL) or systemic anaplastic large cell lymphoma (ALCL) who relapsed after achieving complete or partial remission (CR or PR) with initial brentuximab vedotin therapy in a previous study (ClinicalTrials.gov NC...
Oxime extractants 3-tert-butyl-2-hydroxy-5-methyl benzaldehyde oxime (HL1) and 3-tert-butyl-2-hydroxy-5-methoxy benzaldehyde oxime (HL2) were synthesized and characterized by conventional spectroscopic methods. Suitable lipophilic nature of the prepared extractants allowed examining the ability of these molecules for extr...
The generalization of p-frame in Banach spaces is considered in this paper. The concepts of an $tilde{X}$-frame and a system conjugate to $tilde{X}$-frame were introduced. Analogues of the results on the existence of conjugate system were obtained. The stability of $tilde{X}$-frame having a conjugate system is studied.
PURPOSE Brentuximab vedotin is an antibody-drug conjugate (ADC) that selectively delivers monomethyl auristatin E, an antimicrotubule agent, into CD30-expressing cells. In phase I studies, brentuximab vedotin demonstrated significant activity with a favorable safety profile in patients with relapsed or refractory CD30-positive lymphomas. PATIENTS AND METHODS In this multinational, open-label,...
background : who focuses on developing health literacy (hl) referring to cognitive and social skills. our objectives were to develop a scale for evaluating the hl level of thai childhood overweight, and develop a path model of health behavior (hb) for preventing obesity. study design: a cross-sectional study. methods : this research used a mixed method. overall, 2,000 school students were aged ...
conclusions it was concluded that ihlq might be a practical and useful tool for investigating hl for persian language speakers around the world. since hl is dynamic and its instruments should be regularly revised, further studies are recommended to assess hl with application of ihlq to detect its potential imperfections. results internal consistency and test-retest reliability (icc) of the fact...
The computation of structural failure probability is vital importance in the reliability analysis and may be carried out on the basis of the first-order reliability method using various mathematical iterative approaches such as Hasofer-Lind and Rackwitz-Fiessler (HL-RF). This method may not converge in complicated problems and nonlinear limit state functions, which usually shows itself in the f...
the computation of structural failure probability is vital importance in the reliability analysis and may be carried out on the basis of the first-order reliability method using various mathematical iterative approaches such as hasofer-lind and rackwitz-fiessler (hl-rf). this method may not converge in complicated problems and nonlinear limit state functions, which usually shows itself in the f...
We have developed a group of water-soluble drug conjugates in which daunomycin (Dau) is coupled to cationic, amphoteric or anionic branched polypeptides and a new conjugate containing a cationic polypeptide carrier modified with a cell penetrating octaarginine. We investigated in vitro physiological activity of these conjugates in several aspects: in vitro cytotoxicity and cytostatic effect, ad...
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