Porokeratoses are uncommon hereditary or acquired keratinization disorders due to abnormal clones of keratinocytes in the epidermis. Porokeratoses have several clinical features which may occur simultaneously. A rare type is verrucous porokeratosis (VPK). Herein, we present a 47-year-old man with a 4-year history of perianal verrucous lesions and one year history of annular pruritic lesions on ...

Punctate palmoplantar keratoderma (PPPK) is a rare entity with an estimated prevalence rate of 1.17/100,000. PPPK usually presents with bilateral asymptomatic, tiny, hyperkeratotic punctate papules and plaques on the palmoplantar surface. Among the PPPK varieties, the linear presentation is much rarer, and so far there have been only 3 case reports. Here, we report the case of a 27-year-old fem...

Porokeratoses represent a group of uncommon, acquired or hereditary dermatoses, due to a keratinization disorder whose origin is still unclear; they could be due to the expansion of a clone of abnormal epidermal keratinocytes. Several clinical forms exist, of which the most common is disseminated superficial actinic porokeratosis; other forms include Mibelli, disseminated superficial, linear, p...

Porokeratosis is the common name of several diseases of unknown pathogenesis, which are similar in clinical appearance. It was first described in 1893 and was thought to be a disorder of sweat glands, hence the name porokeratosis. The lesion that can be found in all cases is annular, with atrophic center, and hyperkeratotic outer ring. Cases of porokeratosis have been linked with genetic herita...

Porokeratosis is a rare genodermatosis based on chronic keratinization disorder histologically characterized by the presence of a cornoid lamella and various clinical manifestations. Five most commonly described types of poroketarosis are porokeratosis of Mibelli or ”classic” porokeratosis, disseminated superfi cial actinic porokeratosis, disseminated palmoplantar porokeratosis, linear porokera...

A 45-year-old white man with a medical history that was remarkable for human immunodeficiency virus and AIDS complicated by Kaposi sarcoma presented with a 14-year history of a recurring scaly, pruritic lesion on the dorsal aspect of his left shin. The lesion was refractory to treatment with topical corticosteroids, tazarotene, salicylic acid, and various emollient and keratolytic creams. Recen...

Abstract A 45-year-old man with a history of psoriasis presented to our male genital dermatology clinic several-year pruritic, painful, hyperkeratotic red–brown plaques on both buttocks. He had previously been treated unsuccessfully cryotherapy and topical imiquimod podophyllotoxin for suspected condyloma acuminata. 4-mm punch biopsy from the left buttock showed hyperkeratosis, hypergranulosis,...

Porokeratosis is a disorder of epidermal keratinization characterized clinically by a distinctive ridge-like border, and histologically by cornoid lamellae. The known clinical variants of porokeratosis are: classic porokeratosis of Mibelli, disseminated superficial (actinic) porokeratosis (DSAP), porokeratosis palmaris et plantaris disseminata, linear porokeratosis and punctate porokeratosis. I...

Skin in the tadpole of anuran larvae prior to metamorphosis is composed of two layers of epidermal cells (Leeson and Threadgold, 1961; Chapman and Dawson, 1961; Edds and Sweeny, 1960, 1962), a laminated basement lamella, and a layer of dermal mesenchyme cells apposed to the underside of the basement lamella. An adepidermal space and membrane (Salpeter and Singer, 1959, 1960) separate epidermis ...