The nervous system is a complex, highly-ordered, integrated network of cells. Dispersed cultures of neurons enable investigations into intrinsic cellular functions without the complexities inherent in the intact nervous system. This culture process generates a homogeneously dispersed population that is assumed to be spatially random. Despite the vast number of studies utilizing dispersed neuron...

Design patterns represent solutions to problems that have been proved to be useful in different contexts and can be reused. An experienced programmer can choose a suitable pattern for a given problem effectively. However, for an inexperienced programmer this is a very hard task. We propose a multi-agent system that supports programmers in choosing the design pattern suitable for the given probl...

Design patterns represent reusable solutions to problems that have been proved to be useful in different contexts. An experienced programmer can choose a suitable pattern for a given problem effectively. However, for an inexperienced programmer this is a very hard task. We propose a multi-agent system that supports programmers in choosing the design pattern suitable for a given problem. Persona...

With the global village approaching a new era of aesthetic economy powered by culture creative, every country is actively seeking inspirational resources for culturally creative product design. Chinese traditional poetry, full of expression created with poets’ fascinating words and still highly appreciated today, carries not only our predecessors’ wisdom but also principles which correspond to ...

The culture media optimization is an inevitable part of upstream process development in therapeutic monoclonal antibodies (mAbs) production. The quality by design (QbD) approach defines the assured quality of the final product through the development stage. An important step in QbD is determination of the main quality attributes. During the media optimization, some of the main quality attribute...

background: the human leukocyte antigen (hla) matching between organ donor and recipient is an acceptable strategy in clinical transplantation since 1964. however, in bone marrow transplantation, finding matched donors is often problematic. thus new method for down regulation of hla can be an alternative strategy to solve this problem. objective: to examine the effect of serum starvation on hla...

two different growth media, namely complex and defined media, were used to examine establishment of steady-state conditions in phosphate-limited culture system of saccharomyces cerevisiae cen.pk113-5d strain. using the defined growth medium, it was possible to obtain steady state condition in the continuous culture. the effect of phosphate concentration on the growth of s. cerevisiae in phospha...