نتایج جستجو برای: cyanamides
تعداد نتایج: 55 فیلتر نتایج به سال:
Abstract Metal-catalyzed [2+2+2] cycloaddition is a powerful tool that allows rapid construction of functionalized 6-membered carbo- and heterocycles in single step through an atom-economical process with high functional group tolerance. The reaction usually regio- chemoselective although selectivity issues can still be challenging for intermolecular reactions involving the cross-[2+2+2] two or...
A valuable pharmacophore, the 2-aminoimidazole moiety, can be accessed with a variety of substitution patterns through an addition-hydroamination-isomerization sequence (see scheme; R(1),R(4),R(5)=alkyl; R(3)=alkyl, aryl; R(2)=H, alkyl, aryl). The synthesis of the propargyl cyanamide precursors through a three-component coupling enables the preparation of this important heterocyclic core struct...
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